Zach Reitman MD, PhD is Assistant Professor of Radiation Oncology, Pathology, and Neurosurgery at Duke University. He completed an MD/PhD at Duke in 2014, and a Radiation Oncology residency and research fellowship at Harvard, the Dana-Farber Cancer Institute, and Broad Institute in 2019. He is a physician-scientist and sees brain tumor patients in the Duke Radiation Oncology clinic. Dr. Reitman's research lab has received more than $4M in funding from the NIH, philanthropic, and foundational sources, including an Alex's Lemonade Stand Foundation A Award. His work has identified frequent brain tumor mutations, defined brain tumor heterogeneity, and identified novel potential therapeutic approaches leading to lead-author publications in journals such as PNAS, Nature Chemical Biology, Journal of Clinical Investigation, Nature Genetics, and Nature Communications.
Talk title: "Brain Tumors, Multi-omics, and Mouse Models"
Short abstract: Dr. Reitman will overview his research career path, including discoveries of frequent brain tumor mutations (IDH1, TERT, ATRX, etc.) during his MD/PhD training in the Hai Yan Lab at Duke that are now used to classify gliomas. He will then discuss his more recent work in the Reitman lab developing novel mouse models to study critical brain tumor driver mutations, and approaches to identify new therapeutic strategies to treat brain tumors.
