Science Pub Corvallis - Virtual

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Natural products and hemp: Under-appreciated sources for COVID-19 therapeutic agents

Richard B. van Breemen, Ph.D.Professor of Pharmaceutical ScienceCollege of Pharmacy, Linus Pauling InstituteGlobal Hemp Innovation CenterOregon State UniversityNatural products account for about half of all drugs currently in use, and 90% of molecules made by nature remain to be evaluated for pharmaceutical activity. Despite this, every major pharmaceutical company has dismantled their natural product drug discovery programs, and the U.S. National Institutes of Health supports very little natural product drug discovery research. Hemp is a particularly rich source of unique natural products, many of which have pharmacological activity. However, the U.S. Government prohibited the propagation of hemp from 1936 until 2014, and many restrictions are still in place. With the passage of the U.S. Farm Bill in 2014, hemp cultivation and hemp-based products rebounded. The COVID-19 pandemic inspired a resurgence in natural products research for the discovery of new antiviral agents, and several laboratories around the world reported that certain cannabinoids from hemp exhibited anti-SARS-CoV-2 activity. Our paper reporting that CBDA, CBGA, and THCA-A from hemp could prevent cell entry and infection by SARS-CoV-2, which was published in the Journal of Natural Products in January 2022, set records for downloads and online views, and was covered by over 400 news agencies around the world.To attend this event in-person at Old World Deli, please use this registration link: https://www.eventbrite.com/e/science-pub-corvallis-tickets-453877960197 For more info visit <a href="https://communications.oregonstate.edu/events/events-and-projects/corvallis-science-pub" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Science Pub Night</a>.Science Pub is sponsored by the <a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__omsi.edu&amp;d=DwMFAg&amp;c=UCja3IwhyjPGYeHcG7oIbg&amp;r=LP4hg5-xePaIMGRKTUluCQ5kc-LbspapePhb68y42PQ&amp;m=yb7izb0ZBFTKNpawp9ide0hpI7ZHKCRKixQ3FRPuIpA&amp;s=GfF1CiVa01FkiI2JmESTiz2S9MdBAsIzN-zA5-xHqQ4&amp;e=" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Oregon Museum of Science and Industry</a>, the <a href="https://www.oldworldcenter.com/" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Old World Deli </a>and <a href="https://urldefense.proofpoint.com/v2/url?u=http-3A__oregonstate.edu_&amp;d=DwMFAg&amp;c=UCja3IwhyjPGYeHcG7oIbg&amp;r=LP4hg5-xePaIMGRKTUluCQ5kc-LbspapePhb68y42PQ&amp;m=yb7izb0ZBFTKNpawp9ide0hpI7ZHKCRKixQ3FRPuIpA&amp;s=Xm83SJfJ-jCMr6JHi8FdF9HdEZrWKZwD8_7W2V9YQ9s&amp;e=" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer">Oregon State University</a>.

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Science Pub Corvallis - Virtual

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