The Centre for Biomolecular Spectroscopy (CBS) at King’s College London brings together advanced instrumentation in a number of biophysical techniques to support advanced studies of biological molecules, from proteins to metabolites, both in basic and medical science, and for projects that translate these advances into clinical understanding and benefit. The CBS provides an inclusive hub for training and research and brings together scientists from a wide range of different fields, within King’s College and external research institutes and industrial partners.
Our symposium seeks to bring together researchers operating at the forefront of structural biology, biophysics and metabolomics, and is an opportunity to showcase exciting new work from our early career researchers.
Our plenary speaker is Prof. Teresa Carlomagno, who will deliver a talk showcasing the application of interdisciplinary approaches that combine and integrate biochemical, biophysical, cellular, and structural biology methods.
This event is open to all KCL Staff, Post-Doctoral Research Assistants and PhD students, as well as external attendees from academia and industry.
Scientific Program
Arrival, Tea/Coffee - 09.45 - 10.30
Session 1 – 10.30 – 12.30
10.30 Welcome Address – Prof Sasi Conte, KCL
10.35 Plenary Speaker – Prof Teresa Carlomagno, University of Birmingham - TBC
11.20 - Dr. Shervin (Sherry) Dokht Sadeghi Nasab, KCL - ‘Application of NMR metabolomics to profile metabolic changes in host-microbiome interactions’
11.35 - Dr. Giancarlo Abis, KCL – ‘Unravelling the RNA binding mechanism of LaRP4A and LaRP4B’
11.50 - Dr. Martin Rees, KCL – ‘In silico design and in vitro characterisation of proteins that bind the massive muscle protein titin’
12:05 - Mr. Yuanyang Xie, KCL - ‘Chiral Plasmonic Particles’
12.20 - Dr. Raul Pacheco Gomez, Malvern Panalytical - ‘A journey through biophysical characterisation at Malvern Panalytical: what can we learn’
Lunch - 12.25 – 13.25
Session 2 – 13.25 – 15.00
13:25 - Dr. Charlie McTernan, Crick Institute/ KCL – ‘How to Build Boxes with Peptides – and How to Figure Out What You’ve Made’
15.55 – Dr. Philipp Heher, KCL – ‘Metabolic Pathomechanisms of Facioscapulohumeral Muscular Dystrophy’
14.10 - Dr. Saima Rehman, KCL – ‘A Unique Host-Microbe Interaction at the Atomic Level: Legionella’s Lcl recruits glycosaminoglycans’
14.25 – Dr. Julie McDonald, Imperial College London – ‘Nutrient competition and metabolite inhibition by the gut microbiota restricts the intestinal growth of carbapenem-resistant Enterobacteriaceae’
14.55 - Dr. Ravindra Chaudhari, NanoTemper - TBC
Tea/ Coffee Break - 15.00 – 15.45
Session 3 – 15.45 – 17.00.
15.45 – Dr. James Stowell, LMB Cambridge – ‘Phosphorylation-dependent tuning of mRNA deadenylation rates’
16.00 - Ms. Zoe Hoare, KCL – ‘Targeting elevated intracellular Na and metabolic reprogramming in heart failure’
16.15 - Dr. Susan Vester, KCL ‘Anti-IgD nanobodies as novel tools for studying the biology of immunoglobulins’
16.30 - Dr. Gabi Heller, University College London - ‘Picosecond Dynamics of a Small Molecule in Its Bound State with an Intrinsically Disordered Protein’
Close - 17.00
Sponsors:
Malvern Panalytical
Bruker
