Name: Bioanalytics Workshop
Start: 2017-04-06T09:00:00-04:00
End: 2017-04-07T15:00:00-04:00
Location: Beth Israel Deaconess Medical Center

Bioanalytics Workshop

X-ray Crystallography CoreThe X-ray Crystallography Facility was recently established as a core to serve the needs of investigators in the BIDMC and Harvard Medical School community interested in using structural biology as a tool in their research.

X-Ray Crystallography Core, Gabriel Birrane, PhD

<H2>Learn about measuring binding affinity, protein stability and aggregation from the experts.</H2>
<UL>
<LI>Hear scientific talks by local researchers</LI>
<LI>Discuss how the latest technologies, Microscale Thermophoresis and nanoDSF, help to advance your research</LI>
<LI>Generate data from your own samples </LI>
<LI>Network with your peers from Academia and Industry</LI>
</UL>
<H3> </H3>
<H2>Thursday, April 6</H2>
9:00 am Welcome from Gabriel Birrane, PhD (BIDMC, X-Ray Crystallography Core)
9:10 am Engineering biomolecular nanostructures for enhanced enzyme catalysis: the need for quantitative substrate binding measurements (<A HREF="http://www.engr.ucr.edu/~iwheeldon/home.html" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Dr. Ian Wheeldon</A>, Assistant Professor of Chemical & Environmental Engineering, University of California, Riverside)
9:40 am Cytochrome c oxidase assembly: Characterization of Cu chaperones (Dr. Iulian Trasnea, Postdoctoral Researcher, <A HREF="https://www.bio.upenn.edu/%20" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Department of Biology, University of Pennsylvania</A>)
10:10 am Coffee break
10:30 am Identification of Nrf1 as an ER membrane cholesterol sensor guarding homeostasis. (<A HREF="https://www.hsph.harvard.edu/scott-widenmaier/" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Dr. Scott Widenmaier</A>, Research Fellow, Department of Genetics and Complex Diseases, Harvard School of Public Health)
11:00 am Biologics Stability Screening Has Never Been Faster, Easier & More Fun (Charles Heffern, PhD, NanoTemper)
11:30 am New Applications to Take Your Research to the Next Level (Dinorah Leyva, PhD, NanoTemper)
12:00 pm Lunch available
1:00 pm Breakout Workshops
<UL>
<LI>Sample preparation overview for Microscale Thermophoresis and nanoDSF for new users (Nicole Eckart, PhD, NanoTemper)</LI>
<LI>Experimental work on user samples</LI>
</UL>
5:30 pm <A HREF="http://www.billsbarboston.com/tqebv0g6s0jnxe980olaxh2jbji2wr" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">Bill's Bar</A> (5 Lansdowne St, Boston)
 
<H2>Friday, April 7</H2>
9:00 am Refreshments networking reception
9:30 am Experimental work on user samples
12:00 pm Lunch available
1:00 pm Experimental work on user samples
3:30 pm End of day
 
<H2>Who should attend?</H2>
<H3>Scientists working in:</H3>
<UL>
<LI>Protein purification</LI>
<LI>X-ray or protein crystallography</LI>
<LI>Cryo EM</LI>
<LI>Drug development</LI>
<LI>Formulation development</LI>
<LI>Process development</LI>
</UL>
<H3>Or struggling with:</H3>
<UL>
<LI>Small molecules</LI>
<LI>Therapeutic proteins</LI>
<LI>Sensitive membrane proteins</LI>
</UL>
 
<H2>I want to bring my own samples. What do I need to do?</H2>
For experimental work on <A HREF="https://www.surveymonkey.com/r/thermophoresis" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">binding affinity using Microscale Thermophoresis, fill out this form</A>.
For experimental work on <A HREF="https://www.surveymonkey.com/r/nanoDSF" TARGET="_blank" DATA-MSYS-CLICKTRACK="0" REL="nofollow noopener noreferrer">protein stability and aggregation using nanoDSF, fill out this form</A>.
For questions, please contact Gabriel Birrane, PhD (gbirrane@bidmc.harvard.edu, 617-667-0025)

Bioanalytics Workshop

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