Why Bayesian in Pumas? A wide of priors and error models, both marginal and joint MCMC, and the fastest ODE solvers. Come experience it!

Bayesian Workflow in Pumas

Presented by Pumas-AI, Inc.

This hands-on workshop is designed for novices in Bayesian methods and relatively experienced individuals dealing with pharmacometrics. Pharmaceutical Modelling and Simulation (Pumas) is a domain-specific extension of the Julia differential equation solver libraries for performing analyses of pharmacometric models.  Attendees will learn Bayesian methods and how to build Bayesian PKPD workflows in Pumas.

At the end of the workshop, participants will:

• Gain an understanding of Bayesian methods
• Gain an overview of the Pumas modelling interface
• Learn how to specify priors for parameter values
• Gain an understanding of Markov Chain Monte Carlo sampling methods
• Learn how to perform Bayesian inference for models using Pumas
• Learn how to perform post-processing of results for reporting
• Learn how to perform cross-validation and model selection

June 30, 2023

13:00-14:30 Why Bayesian?

14:30-15:30 Introduction to probability and Bayesian statistics

15:30-15:45 Coffee Break

15:45-17:00 Hands-on: Bayesian Pharmacokinetic Model

July 1, 2023

08:30-09:00 Hands -on: Population Pharmacokinetic Modeling - Overview of Pumas

09:00-10:00 Hierarchical Models in Pumas

10:00-10:15 Coffee Break

10:15-11:15 Hands-on: Bayesian Population Pharmacokinetic Modeling Model

11:15-12:30 Hands-on: Posterior predictions and simulations

12:30-13:30 Lunch Break

13:30-15:30 Markov Chain Monte Carlo and Convergence Diagnostics

15:45-16:00 Coffee Break

16:00-17:00 Hands-on: Cross-validation and model evaluation