A Career Path to Precision Oncology

Academia- Industry Opportunities Group

Beyond the PhD is excited to welcome Dr. Seth Garren, Head of Genomics in Precision Oncology at Sanofi. Come learn about his career path!

Seth Garren is the Head of Genomics in Precision Oncology at Sanofi in Cambridge, MA. Seth earned his bachelor’s degree in Molecular and Cell Biology and his PhD in Biomedical Sciences from the University of Connecticut. His PhD thesis was on the global analysis of gene expression changes in cells infected by the oncogenic mouse polyoma virus. Seth went on to do a postdoc at Massachusetts General Hospital where he developed the ability to profile extracellular vesicles from plasma of cancer patients and applied single cell RNASeq to mouse models perturbed with immune checkpoint blockade to understand immune cell response.
In 2018, Seth joined the NGS Technology Center at Pfizer Kendall Square where he worked to generate transcriptome data in collaboration with Rare Disease, Internal Medicine, and Inflammation &amp; Immunology Research Units. He developed automation protocols for bulk, CITEseq, and Hashed single cell library processing. In 2021 Seth became the co-lead of the NGS Technology Center where he worked on applying bulk, single-cell, and spatial transcriptomics to different targets in the therapeutic area portfolios. This led to identifying treatment based off-target effects for repeat expansion diseases, characterizing immune cells driving fibrosis in non-alcoholic steatohepatitis, and leading the generation of spatial data for different mouse models.
Seth currently leads the US Genomics team in applying bulk, single cell, and spatial omics technologies to drive decision making for multiple project team’s drug candidates as well as profiling drug response and disease progression in patient samples from various cohorts in support of oncology

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A Career Path to Precision Oncology

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A Career Path to Precision Oncology

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