Virtual BTEC Seminar on Lentiviral Manufacturing by Rachel Legmann

NC State University’s Biomanufacturing Training and Education Center (BTEC) has been a trusted provider of biomanufacturing education and hands-on training to university students and industry professionals since 2007. BTEC fuels the biomanufacturing industry by training the next generation of working professionals, hosting seminars and events, offering bioprocess services and more.

BTEC- Biomanufacturing Training & Education Center

Powering the Future of Lentiviral Manufacturing: Continuous Perfusion for in vivo Cell and Gene Therapies
Speaker: Rachel Legmann

The BTEC Seminar Series brings in industry professionals and faculty from all areas of biomanufacturing to showcase new research, trends, methods, and processes. The topics span varying aspects of the biomanufacturing industry including research and development, upstream and downstream manufacturing, process development, quality control and assurance, etc. The seminars are offered in person at BTEC on NC State’s Centennial Campus. A select few will be hosted as live webinars. The talks are free and open to all. This talk will be held virtually via Zoom at http://go.ncsu.edu/btec_seminar Speaker: Rachel Legmann, Senior Director of Technology and Gene Therapy at RepligenTalk Title: Powering the Future of LentiviralManufacturing: Continuous Perfusion for in vivo Cell and Gene TherapiesAbstract: The rapid expansion of in vivo gene and cell therapies is redefining lentiviral vector (LV) manufacturing requirements. Systemic delivery demands significantly higher vector quantities, consistent quality, and cost-effective scalability, which traditional batch-based HEK293 transient transfection platforms were not designed to deliver. This presentation highlights how continuous, scalable perfusion enables a transformative shift in LV manufacturing tailored for in vivo applications. We demonstrate a robust, scalable platform capable of supporting large-scale (up to 2,000 L) commercial manufacturing for in-vivo gene and cell therapies.

<a href="https://btec.ncsu.edu/" title="https://btec.ncsu.edu/" target="_blank" data-msys-clicktrack="0" rel="nofollow noopener noreferrer"> Learn more about BTEC</a> In compliance with the Americans with Disabilities Act, NC State will honor requests for reasonable accommodations made by individuals with disabilities. Please direct accommodation requests to: Leslie Lewis, leslie_lewis@ncsu.edu.

Virtual BTEC Seminar on Lentiviral Manufacturing by Rachel Legmann

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Virtual BTEC Seminar on Lentiviral Manufacturing by Rachel Legmann

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