Workshop on Rapid Prototyping

• Organized by the ShikiFactory100 project - https://www.shikifactory100.eu/
• Hosted by: DSM
  
• Date: February 5, 2020
• Target audience: Industry and academia
• Duration: 1 afternoon

Introduction

The development of economically feasible and sustainable biotechnological processes as alternatives to oil-based chemistry is one of the major goals of bio-based economy. The global chemical industry has initiated a crucial transition from petrochemical processes to bio-based chemical processes.

Metabolic engineering technologies have led to an increasing number of successes over the last decades by engineering and optimizing industrial hosts to competitively produce high-value metabolites. To that end, accelerated reductions of the time from concept to development to scale-up are essential.

In automated robotic platforms, the selection within the design space of biological circuits and biosensors can be optimized, built and tested based on multicriteria objectives that are fed back into the learn and design engines. The high success rate of this rapid design and prototyping of microbially-produced compounds reveals the potential role of biofoundries in leading the sustainable production of next-generation bio-based chemicals.

This workshop does not have hands-on (practical) sessions. Three guests will give a talk about a related topic, each followed by a period of discussion where participants can interact with the speakers.

An 1/2h roundtable discussion will follow the talks.

The workshop will conclude with a demo session of the Onyx platform delivered by Inscripta.

Program overview (14:00 - 17:00)

• Welcome

• Talk 1 - Pablo Carbonell (The University of Manchester, SYNBIOCHEM): Rapid prototyping of microbial synthetic pathways for biomanufacturing;

• Talk 2 - Hans Roubos (DSM Biotechnology Center): Rapid prototyping using Design-Build-Test-Learn in industrial biotechnology;

• Talk 3 - Jason T. Gammack (CCO, Inscripta): Digital Genome Engineering: Unlocking the Unlimited Potential of Biology;

• Roundtable discussion - Moderated by Simão Soares (SilicoLife)

• Demo of the Onyx platform - Kim Soerensen (Inscripta)

Other information

• Learn more about the project: http://shikifactory100.eu

• This is a free workshop, participants are expected to stay for the full workshop.

• Accommodation and meals are covered by the participants

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement number 814408.