The third workshop of Mission-Critical Big Data Analytics (MCBDA 2018) is going to take place on May 15-16, 2018 at Prairie View A&M University, Prairie View, TX, USA. This two-day workshop will cover the state-of-the-art research and development in big data analytics, especially for mission-critical applications. There will be keynote speech by invited renowned speakers, and tutorial sessions with hands-on training. Research works of cutting edge research topics in big data will be presented, plus a poster session and a demo session where students will present their works.