NIH Investigator Meeting on Functional Neurocircuits of Interoception

PROGRAM BOOK

https://files.nccih.nih.gov/nih-interoception-pi-meeting-online-program-book-508.pdf

Description:

This meeting will feature seven studies funded by the NIH Blueprint for Neuroscience Research: Functional Neural Circuits of Interoception, as well as selected studies on interoception funded by the subsequent Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease, the NIH BRAIN Initiative, and NIH Director’s Pioneer Award (PA) Program. The focus will be on preclinical functional neural circuit analysis of interoception using multiple mammalian model systems and will discuss:

• Digestive System–Brain Connections

• Pulmonary–Cardiovascular Systems–Brain Connections

• Metabolic, Immune, Muscular, and Multiple Systems–Brain Connections

AGENDA

September 29th, 2022, 11:30 a.m.-5 p.m. ET

11:30–11:35 a.m. Opening Remarks

Dr. David Shurtleff, Deputy Director, NCCIH

11:35–11:55 a.m. Overview and Update of the NIH Interoception Program

Dr. Wen Chen, Branch Chief, Division of Extramural Research, NCCIH

KEYNOTE

11:55 a.m.–12:20 p.m. Biologically Inspired Neurotechnology To Probe Brain-Organ Communication

Dr. Polina O. Anikeeva, Massachusetts Institute of Technology

Progress reports from the PIs of NIH grants (15 minutes per presentation):

12:20–2:30 p.m. Session 1: Digestive System-Brain Connections

(Moderator: Dr. Heike Muenzberg-Gruening; Q & A–10 minutes)

(1) Functional Neural Circuits of Stomach-Brain Interoception

Drs. Zhongming Liu and Jiande Chen, University of Michigan at Ann Arbor

(2) Spinal Sensory Ganglia and Gut Sensation

Dr. Ivan E. de Araujo, Icahn School of Medicine at Mount Sinai

(3) Gut-to-Brain Circuits Underlying Fluid Regulation

Dr. Yuki Oka, California Institute of Technology

(4) Functional Identification of Vagal Sensory Neurons Innervating the Liver

Dr. Young-Hwan Jo, Albert Einstein College of Medicine

2:30-2:35 p.m. BREAK

2:35–3:45 p.m. Session 2: Pulmonary–Cardiovascular Systems–Brain Connections

(Moderator: Dr. Mark Andermann; Q & A–10 minutes)

(1) Dissecting the Interoception Circuit that Controls Airway Constriction

Dr. Xin Sun, University of California, San Diego

(2) Unravelling Lung Interoception and Its Functional Consequence in the Developing Ovine Lung

Drs. Arlin B. Blood and Christopher G. Wilson, Loma Linda University

(3) Dissecting Neural Circuits for Breathing Patterns

Dr. Peng Li, University of Michigan at Ann Arbor

(4) Defining Subsets of Sympathetic Neurons Mediating Cardiac Neurotransmission

Dr. Olujimi A. Ajijola, University of California Los Angeles

3:45–4:55 p.m. Session 3: Metabolic, Immune, Muscular, and Multiple Systems-Brain Connections

(Moderator: Dr. Olujimi Ajijola; Q & A–10 minutes)

(1) Insular Cortex Estimates Current and Future Bodily States

Dr. Mark L. Andermann, Beth Israel Deaconess Medical Center

(2) Metabolic Changes: Connecting Temperature Sensing Neurons to Sympathetic Adipose Tissue Stimulation

Dr. Heike Muenzberg-Gruening, LSU Pennington Biomedical Research Center

(3) Functional Peripheral and Central Vagal Neural Circuits of Interoception Inhibiting Pain

Dr. Yu Shin Kim, University of Texas Health Science Center and Dr. Man-kyo Chung, University of Maryland Baltimore

(4) Descending Innervation and Control of Internal Organ Function

Dr. Rui M. Costa, Allen Brain Institute

4:55–5:00 p.m. Closing Remarks

Dr. Rita Valentino, Director, Division of Neuroscience and Behavior, NIDA

5:00 p.m. Adjourn

Reasonable Accommodation

Sign language interpreting services are available upon request. Individuals who need interpreting services and/or other reasonable accommodations to participate in this event should contact the nccihblueprintintero@mail.nih.gov by September 19, 2022.

Questions during the event:

Please send your questions to nccihblueprintintero@mail.nih.gov during the event.