Neurodevelopmental Pathways in the FMR1 Premutation

Presented by Jane E. Roberts, PhD

Jane E. Roberts, PhD, is a Carolina Distinguished Professor of Psychology at the University of South Carolina. She is an internationally recognized expert in developmental psychopathology and directs the Neurodevelopmental Disorders Lab, leading NIH-funded studies that have transformed understanding of early brain-behavior pathways and informed targeted interventions.

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About This Event

This talk will examine developmental trajectories associated with the FMR1 premutation from infancy through adulthood. Drawing on longitudinal data from early childhood (6 months to 6 years), I will highlight emerging patterns in neurodevelopment, social communication, and physiological regulation that may shape later adaptive outcomes. Findings will be integrated with evidence from adult studies to illustrate both continuity and divergence across the lifespan. Together, these results provide new insights into the profile and mechanisms linking early neurodevelopmental processes to lifespan risk and resilience in individuals with the FMR1 premutation.

Learning Objectives

• Differentiate early neurodevelopmental patterns observed in infants and young children (6 months to 6 years) with the FMR1 premutation from typical developmental trajectories
• Evaluate genetic, neurobiological, and environmental mechanisms that contribute to variability in risk and resilience among individuals with the FMR1 premutation
• Apply a lifespan developmental framework to inform research design and clinical decision-making in FMR1-associated and related neurodevelopmental conditions

About the Visiting Professor Lecture Series

The Child Mind Institute Visiting Professor Lecture Series invites leaders in the field of child and adolescent mental health to talk about the latest research and treatment protocols. All events are open to the public. Continuing medical education (CME) credits for psychiatrists and continuing education (CE) credits for psychologists and social workers are available to registered course participants. Learn more.