Bionano Genomics Lunch and Learn at UCI:

Friday, June 14th | 12:00 pm - 1:00 pm

Sprague Hall | Room 105

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Next-Generation Cytogenomics: High-throughput Mapping of Structural Variation in Genetic Disease

The promise of personalized medicine remains elusive, because no single technology can comprehensively detect all of the genomic rearrangements. Bionano High-throughput optical mapping utilizes long reads to elucidate these structural variations.

This seminar will describe how the Bionano Saphyr ® platform enables a genome wide direct visualization of chromosomal abnormalities, with much higher sensitivity and precision than sequencing-based methods. During this seminar, we will:

• Review how Bionano optical mapping technology elucidates genomic rearrangements in cancer and genetic disease that are missed by NGS and cytogenetic methods.
• Describe the multitude of structural variants (SVs) that can be detected with up to 99% sensitivity, in as little as 5% allele fraction, such as insertions, deletions, inversions, and balanced translocations.
• Share examples of how the Bionano Saphyr system is enabling novel insights into the molecular drivers of rare diseases as well as solid and hematologic cancers.

RSVP Now!

Questions? Please contact Heather Mashhoodi

hmashhoodi@bionanogenomics.com

For Research Use Only. Not for use in diagnostic procedures.

About Bionano Genomics

Bionano is a life sciences instrumentation company in the genome analysis space. The Company develops and markets the Saphyr system, a platform for ultra-sensitive and ultra-specific structural variation detection that enables researchers and clinicians to accelerate the search for new diagnostics and therapeutic targets and to streamline the study of changes in chromosomes, which is known as cytogenetics. The Saphyr system comprises an instrument, chip consumables, reagents and a suite of data analysis tools.