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Better Leads, Better Drugs - Innovation in Screening Libraries

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Joseph B. Martin Conference Centre Harvard Medical School

77 Avenue Louis Pasteur

Boston, MA 02115

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The Academic Drug Discovery Consortium invites you to hear about the latest ideas in small-molecule library development at, “Better Leads, Better Drugs: Innovations in Screening Libraries.”

Scientists engaged in drug discovery and chemical biology know that a screen is only as good as the molecules that go into it. But with the vast potential chemical space, how do you decide what to include in your virtual, high-throughput, or fragment-based screens? This event will bring together drug-seekers from academia and industry focused on the application of new technologies and computational tools to tackle this question in order to deliver higher quality leads.

This 1.5-day meeting will create a dynamic, interactive environment for presentations and discussion, and also includes a ½-day networking session for one on one partnering meetings between participants and round table discussions on key topics Sharing libraries among academics; Informatics including data management flow; Virtual screening software tools and open source software.

Exhibition and sponsorship

An exhibition will take place alongside the conference during refreshment breaks for companies and related organisations who may wish to exhibit. For further information and prices, please email: jayshree.mistry0615@gmail.com

Note: Spaces are limited so early application to secure space for your stand is recommended.


Posters are encouraged. Relevant topics include chemical methodology for library synthesis, design of innovative chemical libraries using computational and experimental approaches, and case studies demonstrating the value of a designed library. Please submit a one-page abstract to jayshree.mistry0615@gmail.com by 15th March 2019 with" Better drugs, Better leads - poster abstract" in the subject line.

Confirmed Speakers:

DNA-encoded library: Diversity via Building blocks and scaffolds

Yun Ding, GlaxoSmithKline

From DEX Library Design to Preclinical Candidate: Case Study of the Discovery of X-165

Ying Zhang, X-Chem

Innovative chemical libraries to enable public sector drug repurposing, chemical biology, and novel medicinal chemistry

Ajit Jadav, NIH/NCATS

Discovery of novel chemistry for new biology from within a billion compounds you can buy in 6 weeks

John Irwin, UCSF Pharmaceutical Chemistry

Human kinase repurposing strategies for neglected tropical disease drug discovery

Lori Ferrins, Northeastern University

Designing, Curating and NMR Screening New Fragment Libraries for Discovering Small-molecule Drug Leads

Steven LaPlante, University of Quebec, Visiting professor at Broad Institute

Mechanism of action libraries in academic screening

Jeremy Jenkins, Novartis Institute of Biomedical Sciences

Targeted Protein Degradation as a Novel Therapeutic Approach

Stewart Fisher, C4 Therapeutics, Inc.

Biologically-informed focused libraries

Jerry Joyce, Director of the Genomics Institute of the Novartis Research Foundation (GNF)

Title to be confirmed

Kevin McDonnell, BicycleTx

Venue address:


Delegate fees

ADDC Members $150 USD

Non ADDC Members $200 USD

Students Free (No food and drink) (limited number available, once sold out, please purchase a ticket with food and drink voucher or you can register to go onto our waiting list)

Students $60 USD (food and drink voucher)

Delegate fees for Members and non-members includes food and beverage for the one and half day event (breakfast, lunch, and reception) and will be provided with the appropriate vouchers. If you are a student and wish to have the food and beverage package, the fee for the vouchers will be $60.

Hotels nearby:

url: https://protect2.fireeye.com/url?k=b80b8c74-e44be122-b80bab69-0cc47adb57f0-1699f0043bc19239&u=https://www.google.com/maps/d/u/0/viewer?msa=0&ie=UTF8&ll=42.34528700000003%2C-71.10034000000001&spn=0.029562%2C0.054932&z=14&mid=1b8GX3M4LqmrCBA_T18urUJsq7uc

Excellent value B&B, hotels are:

The Beacon Inn (http://www.beaconinn.com)

Organising committee

Chair: Michelle Arkin, UCSF, Chair for ADDC

Co-chair: Caroline Shamu, Harvard Medical School

Stephen Frye, UNC, ADDC

Matthew Hartman, ADDC

Jayshree Mistry, Modgraph Consultants

Aubrey Mendonca, Chemroutes

Yun Ding, GlaxoSmithKline

Steven LaPlante, University of Quebec, Visiting professor Broad Institute

Bernhard Paul, Carinth Consulting, LLC

*The Academic Drug Discovery Consortium is not affiliated with Harvard University, nor is Academic Drug Discovery Consortium a Harvard University program or activity.

Major Sponsor : Day 1

Platinum Sponsors:

Collaborative Drug Discovery

Gold Sponsors:



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Joseph B. Martin Conference Centre Harvard Medical School

77 Avenue Louis Pasteur

Boston, MA 02115

View Map

Refund Policy

Refunds up to 30 days before event

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