$25 – $250
9th Annual 3Rs Symposium

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$25 – $250

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Johns Hopkins School of Medicine

733 N Broadway

Baltimore, MD 21205

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Collaboration to Improve Animal Welfare and Rigorous Results

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Join us for the 9th Annual 3Rs Symposium: Collaboration to Improve Animal Welfare and Rigorous Results, held June 22-24, 2022!

Wed, Jun 22, 2022 and Thurs, Jun 23, 2022 | 8:30 am - 5pm

Fri, Jun 24, 2022 - Workshop (extra ticket required) | 9am - 12pm (time subject to change)

This event has been submitted for RACE Credits.

This symposium will focus on reduction, refinement, and replacement methods to improve laboratory animal welfare while maintaining or improving scientific results. It is jointly organized by the Center for Alternatives to Animal Testing, Johns Hopkins University Bloomberg School of Public Health, the Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, the USDA’s Animal Welfare Information Center (AWIC) at the National Agricultural Library, and the Office of Laboratory Animal Welfare, National Institutes of Health.

Sessions are designed for investigators, laboratory animal veterinarians, care staff, and IACUC members and staff. Residents, students, and postdocs are also welcome!

The sessions on refinements for better science and animal welfare describe cutting-edge advancements in laboratory animal welfare, methods to achieve sound scientific results, and 3Rs success stories. The full agenda can be found below.

There will also be panel discussions on laboratory animal adoption programs and international perspectives on 3Rs implementation in Asia, Africa, and South America, other TBD presentations, and an optional demonstration of refinement techniques.

Please join us as we learn from the speakers and each other! There will be opportunities built into the program for attendees to ask questions, comment, or offer suggestions. We look forward to seeing you there!


In person attendees will need to provide proof of COVID 19 vaccination and masks may be required depending on the pandemic situation.

Lunch will be provide during in person sessions, but not the June 24th add on workshop

Govt, Post-Doc, Resident and Students will be require to provide proof of affiliation.

Questions? Contact Camila S. Januario cjanuar1@jhu.edu

Day 1 - 6/22/2022

8:30 – 8:45 AM ET - Organizers’ Welcome

Session 1: Refinements for Better Science and Better Welfare

Moderator: Kathrin Herrmann

8:45 – 9:45 AM ET | Coordinating the 3Rs and the 3Vs in Animal Research

o Hanno Würbel, University of Bern, Switzerland

9:45 – 10:45: AM ET | How Wild Mouse Gut Microbiota Promote Host Fitness and Makes a Better Model for Immune System Research

o Stephan Rosshart, University Medical Center Freiburg, Germany

10:45 – 11:00 AM ET | Break

11:00 AM – 12:00 PM ET | Mixed Strain Housing Using a Split-plot Design to Promote Reduction and Refinement While Maintaining Statistical Power

o Mike Walker, Canadian Council on Animal Care

12:00 - 12:45 PM ET | Lunch Break

Moderator: Nicolette Petervary

12:45 – 1:45 PM ET | Mouse Models for Infectious Disease Studies: The Collaborative Cross Project and Outbred Strains

o Mark Heise, University of North Carolina Chapel Hill

1:45 – 3:15 PM ET | Keynote Panel Discussion Day 1: What Happens After Research? Discussion of adoption programs.

o Robert Gump, Food and Drug Administration

o Alice Huang, Department of Veterans Affairs

o Jess Izzi, Johns Hopkins University

3:15 – 3:30 PM ET | Break

3:30 – 4:30 PM ET | In-Person Breakout Session

Day 2 - 6/23/2022

Session 2: Collaborations to improve animal welfare and scientific rigor

Moderator: Caroline Krall

8:30 –10:30 AM ET | Keynote Panel Discussion Day 2: Success Stories: International Collaborations to Solve Local Animal Welfare Issues

o 8:30 – 8:50 AM ET | Francis Fakoya, Founder of ACURET, Member of ICLAS Africa Regional Committee

o 8:50 – 9:10 AM ET | Ekaterina Rivera, Vice President of FESSACAL, Secretary-General of ICLAS America Regional Committee

o 9:10 –9:30 AM ET | Qin Chuan, Vice President of AFLAS, President of CALAS, Director of ILAS

o 9:30 –9:50 AM ET | Ouajdi Souilem, President of ATSAL, Tunisian Council Member of ICLAS, Co-chair of ICLAS Africa Regional Committee, President of Ethical Committee on Animal Experimentation in Tunisia

o 9:50 –10:10 AM ET | Montip Gettayacamin Senior Director, Southeast Asia, AAALAC International

10:30 – 10:45 AM ET | Break

10:45 – 11:45 AM ET | NC3Rs Interactive 3Rs Self-Assessment Tools (with demonstration)

o Jessica Eddy NC3Rs

11:45 AM – 12:30 PM ET | Lunch Break

Session 3: Refinements for Better Science and Better Welfare Part 2

Moderator: Jessie Carder

12:30: – 1:30 PM ET | ICCVAM Interagency Initiatives on Consideration and Validation of Alternative Methods

o Nicole Kleinstreuer, NIH, NIEHS

1:30 – 2:30 PM ET | Refinements to Oral Gavage in Mice

o Melanie Warren, Texas A & M University

2:30 – 3:30 PM ET | Implementing Non-aversive Handling in Mice

o Donna L Goldsteen

3:30 – 3:45 PM ET | Break

3:45 – 4:45 PM ET | In-Person Breakout Session

4:45 – 4:55 PM ET | Wrap-up of Symposium

Day 3 - 6/24/2022 Optional Demonstration: Face to face only, preregistration required

Time TBD | How to implement 3R-based change within biomedical research institutions (In person only and requires a separate registration)

o Eric Hutchinson, Caroline Krall, Lydia Hopper, Johns Hopkins University

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Johns Hopkins School of Medicine

733 N Broadway

Baltimore, MD 21205

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