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World Congress on Advanced Structural and Molecular Biology 2018 (pgr)

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Rome-Aurelia, Via Aurelia, Km 8.400 00165



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World Congress on Advanced Structural and Molecular Biology 2018

About Conference
Pulsus Group is an intentionally renowned per reviewed publisher in scientific, technical, and medical journals established in the year 1984 with offices in Ontario, Canada, and Hyderabad, India has acquired Andrew John Publishing and open access journals.com to expand its Open Access Publishing through its 50+ journals in association with 20+ International medical and scientific societies.

PULSUS takes a immense pleasure in inviting all the participants from across the globe to attend "World Congress on Structural and Molecular Biology 2018" on August 22-23,2018 in Rome, Italy, which has rapid keynote displays, Oral talks, Poster presentations and Exhibitions. Advanced Structural Biology 2018 endeavors to bring prominent scientists, Laboratory technicians, Professors, Medical and Industrial professionals, Young researchers, students and business delegates under a roof providing an opportunity to share the knowledge and scientific advancements in the ground of Structural and Molecular Biology influencing the future research.

Structural biology is the study of molecular structure and dynamics of biological macro molecules like proteins and nucleic acids, and how changes in their structures affect their function, and Molecular biology is a branch of biology that deals with the process of replication, transcription, translation and cell function. Current advancements in the development of novel therapies for the various conditions have revolutionized both by clinical practices and research in Structural and Molecular Biology.

Why to attend?

Advanced Structural Biology 2018 will enlighten the public with recent advances in Structural and Molecular Biology around the world and to sharpen the related ideas about Structural Biology and Molecular modeling techniques. According to current statistics, Structural and Molecular Biology will increase to USD 13.1 from USD 2.52 from 2015 to 2025. Pulsus Group is set to shape an International Conference on Advanced Structural and Molecular Biology this year with a interpretation to augment research and endorse awareness aiming in emerging solutions for the challenges encountered. Take advantage of opportunities to collaborate with structural and molecular biologists from around the world. World renowned speakers, the most recent techniques, and the newest updates in structural and molecular biology fields are the trademark of this conference.

Who should attend?

Structural Biologist, Biochemists, Director of Laboratories, Research and Diagnostic Laboratory Professionals, Clinical Fellows, Research Faculty, Academic Professionals, Academic Scientists, Students, Universities, Industrial Professionals, Business Entrepreneurs, Directors/ Managers/ CEO's, Brand Manufactures / Marketers of Consumer Products, Marketing, Advertising and Promotion Agency Executives.

The track category is the heading under which your abstract will be reviewed and later published in the conference printed matters if accepted. During the submission process, you will be asked to select one track category for your abstract.

Track 1 : Structural and Molecular Biology
Structural biology is the study of molecular structure and dynamics of biological macro-molecules like proteins and nucleic acids, and how changes in their structures affect their function. Structural biology is the combination of the principles of molecular biology, biochemistry, and biophysics. Bio-molecules are too small to be viewed by even the advanced microscope. There are many methods followed by the biologist to determine the size of many identical molecules at the same time.
Molecular biology is a branch of biology that deals with the process of replication, transcription, translation and cell function. The center of attraction is where DNA creates RNA and RNA creates protein. By applying the principles of biology, chemistry, and engineering, we can create plenty of chemicals, antibodies, proteins, and enzymes in a better manner. This leads the molecular biology into various disciplines like agricultural molecular biology, medical or pharmaceutical molecular biology, industrial molecular biology and environmental molecular biology.

  • Track 1-1Computational approaches in Structural Biology
  • Track 1-2Forensics
  • Track 1-3Signaling Biology

Track 2 : Synthetic Biology
Synthetic biology is a combination of biology and engineering. Synthetic biology combines various disciplines to build artificial biological systems for research, engineering, and medical application. It is the draft and construction of new biological entities or the redesign of existing biological systems. It is the combination of advances in chemistry, biology, computer science and engineering that enables us to design a product faster, cheaper and with great precision. It is used in many applications like cell transformation, designing proteins, information storage, material production, space exploration, bio-sensors and synthetic life.

  • Track 2-1Synthetic Transcription Factors
  • Track 2-2Modular Protein Assembly
  • Track 2-3DNA Synthesis
  • Track 2-4Modeling

Track 3 : Biochemistry
Biochemistry is a branch of science which deals with the chemical and physicochemical processes and substances which are inside living organisms. It also deals with the structures and physical properties of biological molecules. Biochemistry is closely related to molecular biology, it is a tool which follows and studies about the molecular biology. The latest focus of biochemistry is to find how biological molecules give rise to the processes happening inside the living cells.

  • Track 3-1Immunology
  • Track 3-2Genetics
  • Track 3-3Enzymology
  • Track 3-4Animal Biochemistry
  • Track 3-5Plant Biochemistry
  • Track 3-6Environmental Biochemistry

Track 4 : Molecular Mechanics
Molecular mechanics use the Newtonian mechanics to design the molecular systems. It is used to study the molecule systems ranging from small to large in size and complexity in biological systems with many thousands to millions of atoms. Each molecular mechanics should follow the properties saying that each atom is one particle, each particle has its radius, polarizability, and constant net change, and the bonded interactions are treated as springs. It is used in applications like, to find the force applied to a particle, for energy minimization. Binding constant, protein folding kinetics, active site coordinates and design binding sites are calculated using molecular mechanics in energy minimization.

  • Track 4-1Molecular Dynamics
  • Track 4-2Molecular Mechanics in Energy Minimization
  • Track 4-3Software of Molecular Mechanics
  • Track 4-4Hardware of Molecular Mechanics

Track 5 : Molecular Physics
Molecular biophysics is a quickly evolving discipline in research that combines the concepts in physics, chemistry, engineering, mathematics, and biology. It explains the biological function in terms of molecular structure, structure organization and dynamic behavior at many levels of complexity. It contains the measurement of molecular forces, molecular associations, allosteric interaction, and cable theory. There are many spectroscopy techniques, which is used to understand the structure of important biomolecules and inter-molecular interaction. The molecular simulation gives the microscopic structure with the help of molecular dynamics software. For more accuracy and biological relevance's, additional terms can be added to the computer simulation equation.

  • Track 5-1Spectroscopy in Molecular Biophysics
  • Track 5-2Molecular Simulations in Molecular Biophysics
  • Track 5-3Molecular Association and Measurement of Molecular Forces
  • Track 5-4Biophysical Profile (BPP)

Track 6 : Genetic Informatics
Genetic informatics is a branch of science which is computer-based, which emphasizes on the databases and software developmental tools. The biological phenomena are studied based on the biomolecules and their interactions which lead to a complete metabolism of the organism and in understanding the evolution of life. This helps in explaining the intrinsic cellular studies, genetic factors, genetic diseases, medications and correlation with the other evolutionary species. The databases realm within them, such that the data source of every bio-molecules thus making it easily accessed, managed and updated by the researchers.

  • Track 6-1Protein Structure Prediction
  • Track 6-2Protein Databanks
  • Track 6-3Homology Modeling

Track 7 : Molecular Basis of Disease
With the entire human genome sequenced, it has become easier than it was decades ago to identify the genes that cause the particular disease. Unfortunately, identification of the gene responsible for the disease doesn't lead to the cure. To develop a therapy we need to understand where and when the particular gene will be expressed, and also their functions when they are normal and when they are diseased.

  • Track 7-1Basic Molecular Technique
  • Track 7-2Biochemical Technique
  • Track 7-3Cell biological Technique
  • Track 7-4Structural Analysis
  • Track 7-5Proteomics

Track 8 : Drug Design, Biomarkers
Drug designing is of finding new medications depending upon the biological target. It uses the 3D information about the biomolecules obtained from analytical techniques which is more traceable when there is a high-resolution structure of a target protein bound to a potent ligand to design the drug. Molecular mechanics or molecular dynamics is most often used to estimate the strength of the intermolecular interactions between the molecule and its biological target. Computational methods have geared up in the discovery of a huge number of iterations providing the novel structures.
Biomarkers include tools and technologies that aid in dynamic and powerful approach to understand the spectrum of neurological diseases in knowing the prediction, cause, diagnosis, progression, regression, or outcome of treatment of a disease.

  • Track 8-1Ligand-based Drug Design
  • Track 8-2Structure-based Drug Design
  • Track 8-3Natural History Markers
  • Track 8-4Drug Activity Markers
  • Track 8-5Surrogate/ Diagnostic Biomarkers
  • Track 8-6Molecular Biomarkers

Track 9 : Genome Replication and Translation
Genome is an important field in computational biology in the development of tools for DNA sequence information and analysis, gene mapping, genetic variation, complex trait mapping, predict protein sequence and structure. Next Generation sequencing results in large amounts of long or short DNA reads requiring assembly process to generate the complete genome sequence. In future, there are possibilities for the development and maintenance of databases of genomic, which includes new tools for annotating complex genomes to expand their utility.

  • Track 9-1Sequencing and Mapping
  • Track 9-2Assembly
  • Track 9-3Annotation
  • Track 9-4Alteration

Track 10 : Bio-chemical Processes
Experimental and computational approaches are combined and used to gain the molecular understanding of fundamental biological mechanisms and to design small molecule probes that can perturb biological pathways in informative and potentially therapeutic ways. Developing and applying experimental and computational approaches to elucidate the molecular structure, design novel molecules, and study complex biological processes.

  • Track 10-1Chemical Probes
  • Track 10-2Structure and Mechanism of Macromolecular Complexes
  • Track 10-3Computational Methods of Chemical Biology
  • Track 10-4Single Molecule Techniques

Track 11 : Structural Virology
Viruses show different morphologies in their shapes and sizes. These are smaller in structures than the bacteria. These are simpler as an individual, but when formed as a group they are exceptionally diverse both in replication strategies and structures. Many viruses are important human pathogens. Many techniques such as x-ray crystallography, NMR and cryo-EM are used to determine viral structures. These structure in-turns are used to develop anti-viral drugs and vaccines.

  • Track 11-1Solution NMR Spectroscopy
  • Track 11-2Cryo-electron Tomography
  • Track 11-3X-ray Crystallography for Viruses
  • Track 11-4Foci Formation
  • Track 11-5Hemagglutination
  • Track 11-6Plague Assay

Track 12 : Molecular Biology Methods and Techniques
Molecular biology deals with the structure and function of macromolecules and also about the interaction between DNA, RNA, protein and its biosynthesis. The different methods in molecular biology are hemacytometer cell counter, restriction enzyme digest, DNA ligation, transfection, western blot, plasmid purification, electroporation, heat shock method, and ELISA. There are various techniques used in molecular biology.

  • Track 12-1Molecular Cloning
  • Track 12-2Polymerase Chain Reaction
  • Track 12-3Gel Electrophoresis
  • Track 12-4Maromolecular Blotting and Probing
  • Track 12-5Microarrays
  • Track 12-6DNA Sequencing
  • Track 12-7Gene Delivery

Track 13 : Structural Biology Techniques
A change in the structure of molecules will cause a change in their functions too. By knowing about the functions for each structural change, it can be used in future for research purposes. There are various techniques used to study the functions when the structures are changed.

  • Track 13-1Advanced Mass Spectroscopy
  • Track 13-2Electron Microscopy
  • Track 13-3Spectroscopy
  • Track 13-4Surface Plasmon Response

Track 14 : Applications of Structural Molecular Biology
Structural molecular biology has a tremendous application in the study of molecules affecting the living beings. The study of the molecules and the changes in the functions due to change in their structure are used in many applications. They are used under three aspects of biophysical methods and instrumentation, their application to biological structure problems, and derivation of structural information and insights. They are used in many areas..

  • Track 14-1Molecular Application
  • Track 14-2Biotechnology
  • Track 14-3Computational Biology
  • Track 14-4Structural and Biophysical Biology

Track 15 : Scientific Techniques
Scientific technique is a generic process that combines the scientific method with a formal process to solve any type of problem, i.e., it is used to find the concentration of a molecule in a chemical compound or element. Structure probing biochemical techniques determines these biomolecular structures in vast numbers of the same identical molecules at once. Scientists use them to study the native states of biomolecules. Few of the best methods determining the structures are X-ray crystallography, Cryo-Electron Microscopy, and Nuclear Magnetic Resonance.

  • Track 15-1Macromolecular Crystallography Proteolysis
  • Track 15-2Multiangle Light Scattering
  • Track 15-3Small Angle Scattering
  • Track 15-4Ultrafast Laser Spectroscopy
  • Track 15-5Electron Paramagnetic Resonance
  • Track 15-6Mass Spectrometry
  • Track 15-7Dual Polarization Interferometry

Track 16 : Nuclear Magnetic Resonance Spectroscopy and Mass Spectrometry
NMR is a method used to obtain information about the structure and dynamics of proteins, nucleic acids, and their complexes. Structure determination by NMR spectroscopy consists of several phases, where each phase has a separate set of highly specialized techniques. The samples are prepared, measured, suitable methods are applied, and the structure is calculated and validated. NMR depends upon the quantum mechanical properties of a nucleus of an atom. Currently, most of the samples are tested in a solution like water, but researchers are going on to work with solid samples too. It is an analytical technique that ionizes chemical species and classifies the ions based on their mass to charge ratio. It measures the masses within a sample.

Mass spectrometry is used in many fields and is applied to pure samples as well as complex mixtures. Mass Spectrometry is used in both qualitative and quantitative ways. This technique is used to identify the unknown compounds, determining the isotopic composition of elements in a molecule and determining the structure of a compound by observing its fragmentation. Some of the applications are trace gas analysis, pharmacokinetics, protein characterization, space exploration, respired gas monitor and preparative mass spectrometry.

  • Track 16-1Solid State Nuclear Magnetic Spectroscopy
  • Track 16-2Multi-dimensional Spectroscopy
  • Track 16-3Fourier Transform Spectroscopy
  • Track 16-4Correlation Spectroscopy
  • Track 16-5Biomolecular NMR Spectroscopy

Track 17 : Crystallography
Crystallography deals with the structure and properties of crystals. It is used to determine the arrangements of atoms in the crystalline solids. Now crystallography depends on analysis of the diffraction patterns of the sample targeted by the beam of some type, mostly x-ray. The most commonly used radiations are x-ray, neutrons, and electrons. To acquire the spatial arrangement of an atom, the radiation should be of shorter wavelength.

  • Track 17-1Xray Crystallography
  • Track 17-2Neutron Crystallography
  • Track 17-3Electron Crystallography
  • Track 17-4Protein Crystallography

Track 18 : Chromatography Techniques
Chromatography is a technique done in laboratories for separation of the mixture. Each particle in a mixture has its own speed of movement, which causes them to separate when dissolved in some fluid. There are two phases, such as mobile phase and stationary phase.The mobile phase is where the mixture is dissolved, and the stationary phase is through which the mixture is carried. The separation is based on these two phases differential partitioning.

  • Track 18-1Shape of Bed
  • Track 18-2Physical State of Mobile Phase
  • Track 18-3Separation Mechanisms
  • Track 18-4Modified or Specialized Chromatography

Track 19 : Clinical Application
The various molecular and structural biology methods are analyzed and used in clinical to treat the infections or injuries. By analyzing and comparing the structure and function of the molecule being affected and non-affected, that is by using the various structural and molecular methods and techniques, the mode and level of injury are found and treated.

  • Track 19-1In Radiation Oncology
  • Track 19-2Diagnosis of Infectious Disease
  • Track 19-3Cancer Research

Track 20 : The Latest Trends in Structural and Molecular Biology
Development of advanced technology helps in disease prevention and better treatment. The technology for drug design, tool development, and imaging technologies are the recent advancements in this field. The latest trends in this field are polymerase chain reaction(PCR), cycle sequencing, pulsed-field gel electrophorosis (PFGE), subtractive hybridization, oligoribonucleotide technology or automated DNA hybridization.

  • Track 20-1Cycle Sequencing
  • Track 20-2Subtractive Hybridization
  • Track 20-3Automated DNA Hybridization
  • Track 20-4PFGE
  • Track 20-5Structure Determination
  • Track 20-6Technology Advances in Existing Methods

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