€187.71 – €436.42

Workshop on PB-QSP, the future of QSP with PK-Sim & MoBi (OSP Suite)

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Freys Hotel

Bryggargatan 12

101 31 Stockholm

Sweden

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Event description

Description

esqLABS is running a one-day hands-on PK-Sim® & MoBi® workshop on integrating PBPK with QSP on Saturday 15th of June at the Freys Hotel in Stockholm, Sweden (after the PAGE Meeting). The workshop covers concepts and application of combining PK-Sim, MoBi and R to build your very own digital platforms for the prediction of clinical trial outcomes by leveraging physiological and mechanistic knowledge to translate early in-vitro and preclinical outcomes to the clinic. During hands-on exercises you will learn how to:

  • Build a PBPK model for biologics in PK-Sim and compare to observed data
  • Integrate mechanism-based pharmacodynamics in MoBi
  • Conduct parameter identifications in PK-Sim and MoBi
  • Simulate and analyze your PBPK-QSP model in R

This workshop will be held by the consultants and scientists from esqlabs GmbH with extensive experience in the use of PK-Sim® & MoBi® in all application areas.

While the workshop does not require any prior experience with PK-Sim® & MoBi®, many topics will be of interest even for advanced users.

The workshop is currently restricted to 30 participants.

AGENDA

As a use-case for above learnings, we will develop a PB-QSP model for therapeutic proteins. We will model naked antibody pre-treatment (nAb) of antibody-drug conjugates (ADC) for the treatment of tumor growth, in detail (preliminary agenda):

Agenda PAGE PB-QSP Workshop PK-Sim MoBi

PREPARATION

  • BRING YOUR OWN LAPTOPS! We will be doing hands-on work!
  • To download the software, please click here
  • Download & install the R distribution (Ver 3.5) from here
  • Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here
  • For starters, please check out the tutorial site (videos & hands-on) here



Best Regards,

Stephan Schaller
(Managing Director, esqLABS GmbH)

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Date and Time

Location

Freys Hotel

Bryggargatan 12

101 31 Stockholm

Sweden

View Map

Refund Policy

Refunds up to 30 days before event

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