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Targeting Epigenetic Mechanisms: Challenges and Solutions

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Ontario Institute for Cancer Research

661 University Avenue

West Tower, Suite 510

Toronto, ON M5G0A3

Canada

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BioLab at the Ontario Institute for Cancer Research (OICR) and Diogenode will co-host a free educational seminar on Targeting Epigenetic Mec

About this Event

Geoffrey Berguet, M.Sc., Bio-engineer, Business Development Manager, Diagenode

Geoffrey has been working for more than eight years at Diagenode. He started as a field application specialist for Diagenode’s automated instrument (IP-Star®) for ChIP-seq. Later he became a product manager for automation and started the Epigenomics Service platform. Recently, Geoffrey moved to Diagenode’s US office to help developing the strategy for industry and key accounts with a focus on epigenomic services for oncology, immunology and neuroscience.

Epigenetic reprogramming in cancer occurs at multiple cellular levels including nuclear organization and nucleosome positioning, DNA methylation, modification of histones, alteration of epigenetic regulators such as transcription factor binding, and non-coding RNA, such as microRNA. Accurate use of versatile instrumentation and tools is essential for studying epigenetics.

Join us to learn more about Diagenode’s epigenomics profiling platform, from sample preparation and innovative nucleic acids shearing instrumentation to chromatin Immunoprecipitation-, DNA methylation-, RNA-seq assays and analysis.

Learning objectives:

1. Get cutting-edge knowledge of epigenetics:

- Chromatin Immunoprecipitation: ATAC-seq, ChIP-seq, ChIPmentation

- DNA methylation: WGBS, RRBS, EPIC array, Targeted, MeDIP-seq

- RNA-seq: miRNA, small RNA, mRNA, total RNA

2. Learning on assay applications and use of nucleic acids shearing instrumentation

1 – 2 p.m. Targeting Epigenetic Mechanisms: Challenges and Solutions

Geoffrey Berguet, MSc, Diagenode

Epigenetic reprogramming in cancer occurs at multiple cellular levels including nuclear organization and nucleosome positioning, DNA methylation, modification of histones, alteration of epigenetic regulators such as transcription factor binding, and non-coding RNA, such as microRNA. Accurate use of versatile instrumentation and tools is essential for studying epigenetics.

The seminar will introduce Diagenode’s epigenomics profiling platform, from sample preparation and innovative nucleic acids shearing instrumentation to chromatin Immunoprecipitation-, DNA methylation-, RNA-seq assays and analysis.

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Ontario Institute for Cancer Research

661 University Avenue

West Tower, Suite 510

Toronto, ON M5G0A3

Canada

View Map

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