Opportunities and challenges in Single-Cell Biology

The cell is the basic unit of life, however only very recent technological advancements that span from single cell multi-omics to high-throughput live imaging have allowed scientists to actually observe and measure complex biological processes, and new signalling pathways at single cell level. These new multidimensional approaches reveal that no two cells are exactly the same and subtle changes that make each one unique are emerging.

The increased resolution and the complexity of the analysis are shaking our perspective on basic biological processes and are revealing new molecular networks. This scientific revolution can pave the way for a novel interpretation of the cell biology, especially those at the basis of complex phenotypes.

The second edition of this free workshop focuses on the new opportunities and challenges that the "single-cell revolution" brings at the experimental, technological and data-analysis levels, but also on novel paradigms in modern biology. Condensed in one day program, the speakers will present new biological insights find out while moving from “too many “to “one”.

Topics: Single Cell Sequencing, Bioinformatics, Immunology, Imaging

Registration is FREE but each participant must register with an individual email address

One ticket one person.

For any question send an email to the following address:

singlecellworkshop@gmail.com

CONFIRMED SPEAKERS

• Dr Davide Cittaro,  Center for Translational Genomics and Bioinformatics, San Raffaele Hospital

• Dr Gennaro Gambardella,  Genomic Medicine, Telethon Institute of Genomics and Medicine

• Dr Sonia Gavasso, University of Bergen, Bergen, Norway

• Dr Marco Cosentino Lagomarsino,  IFOM, The FIRC Institute of Molecular Oncology, and Physics Department, University of Milan

• Dr Enrico Lugli,  Translational Immunology Lab, Humanitas Clinical and Research Center

• Dr Mirela Kuka,  Dynamics of Immune Responses Unit, San Raffaele Hospital

• Prof Giulio Pavesi, Dept. of Bioscience, University of Milan

• Dr Simone Picelli, Single Cell Genomics Platform, Institute Ophthalmology Basel, IOB

• Dr Ricardo Miragaia,  AstraZeneca, Cambridge

• Prof Giuseppe Testa, Stem Cell Epigenetics Unit, Istituto Europeo di Oncologia, IEO

• Dr Federica Zanardi, Bioinformatics Core Unit, IFOM, The FIRC Institute of Molecular Oncology

PROGRAM

• 9:30 - 10:00 Giulio Pavesi,  Dept. of Bioscience, University of Milan
  Single Cell Transcriptomics (as of Today)

• 10:00 - 10:30  Davide Cittaro,  Translational Genomics and Bioinformatics, San Raffaele Hospital
  Beyond the plate: droplet-based integrative analysis of genome and epigenome of thousands cells

• 10:30 - 10:50 Gennaro Gambardella,  Genomic Medicine, Telethon Institute of Genomics and Medicine
  Single-cell transcriptomics to reveal biomarkers and mechanisms of drug sensitivity in breast cancer cells

• 11:20 - 11:40 Mirela Kuka,  Dynamics of Immune Responses Unit, San Raffaele Hospital
  Single-Cell Technology Approaches to Unravel Immune Cell Dynamics

• 11:40 - 11:55 Luca Mazzitelli, 10x Genomics
  

• 11:55 - 12:25 Giuseppe Testa, Stem Cell Epigenetics Unit, Istituto Europeo di Oncologia, IEO
  

• 13:50 - 14:20 Enrico Lugli,  Translational Immunology Lab, Humanitas Clinical and Research Center
  Anti-tumor T cell immunity at single cell resolution

• 14:20 - 14:40 Ricardo Miragaia,  AstraZeneca
  Tissue Adaptation of Regulatory T cells

• 14:40 - 14:50 Roberto Spada,  Fluidigm
  Unravelling the complexity of biology with high parameter research

• 14:50 - 15:10 Sonia Gavasso, University of Bergen, Norway
  Immune monitoring by mass cytometry: system study at single cell resolution

• 15:10 - 15:30 Simone Picelli, Single Cell Genomics Platform, Institute Ophthalmology Basel, IOB
  Single-cell sequencing as a tool to tease apart the complexity of the Human Eye

• 16:10 - 16:40 Marco Cosentino Lagomarsino,  IFOM, The FIRC Institute of Molecular Oncology, and Physics Department, University of Milan
  Quantifying cell-cycle progression in single cells

• 16:40 - 16:55 Daniel Liber,  Takara Bio
  ICELL8 cx: The open and high-throughput platform for single-cell genomics

• 16:55 - 17:15 Federica Zanardi,  Bioinformatics Core Unit, IFOM, The FIRC Institute of Molecular Oncology
  Unraveling in-vitro clonal selection by scRNA-seq

17:30 - t.b.d. Social Drinks

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Coffee and Lunch breaks are kindly offered by our sponsors:

• 10X Genomics

• Alphatest

• Bio-Rad

• Carlo Erba

• D.B.A. Italia

• Diatech Labline

• Euroclone

• Fluidigm

• Genespin

• Thermofisher

• Fondazione Umberto Veronesi

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This workshop is organized by:

• Department of Life Sciences and Systems Biology,  University of Turin @ Valentina Proserpio

• IFOM the FIRC Institute of Molecular Oncology @ Fabio Iannelli

• Phisycs Department, University of Turin @ Matteo Osella

• Italian Institute for Gemomic Medicine (IIGM) @ Valentina Proserpio, Matteo Cereda, Luigia Pace

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