€528.49 – €792.24

QSPC2020: PBPK & QSP with PK-Sim & MoBi (OSP Suite)

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Location

QSPC2020

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Leiden

Netherlands

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Refunds up to 7 days before event

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Description

esqLABS is running two hands-on PK-Sim® & MoBi® workshops on PBPK and PBPK-based QSP on Tuesday and Saturday 21st and 25th of April 2020 as (pre & post) satellite meetings to the QSPC 2020 Meeting in Leiden, Netherlands.

Learn to create your very own PBPK and PB-QSP platforms by combining PK-Sim, MoBi, and R. The workshop will commence with a brief introduction to the basic concepts of PBPK. We will quickly switch to hands-on exercises in which we will cover use-cases for DDI, pediatric analyses and PBPK/PD for biologics.

Within the two workshops, you will learn how to:

Workshop 1 / Day 1:

  • Build a PBPK model in PK-Sim and compare simulations with observed data
  • Learn how to model drug-drug interactions in PK-Sim (DDI)
  • Learn how to consider age-dependency in PK-Sim (Pediatric Analyses)
  • Conduct population simulations in PK-Sim and MoBi

Workshop 2 / Day 2:

  • Integrate mechanism-based pharmacodynamics in MoBi
  • Conduct parameter identifications in PK-Sim and MoBi
  • Simulate and analyze your PBPK-QSP model in R

The two workshops will be held by consultants and scientists from esqlabs GmbH who have extensive experience in the use of PK-Sim® & MoBi® in all application areas.

While the workshop does not require any prior experience with PK-Sim® & MoBi®, many topics will be of interest even for advanced users.

LOCATION

Workshop 1 PBPK (April 21, 2020)

Golden Tulip Hotel
Schipholweg 3
2316 XB Leiden, Netherlands

Workshop 2 PB-QSP (April 25, 2020)

Fletcher Wellness-Hotel Leiden
Bargelaan 180
2333 CW Leiden, Netherlands

REGISTRATION

You can register for each workshop (days) separately or for both at a reduced price.

Each workshop day is currently restricted to 15 participants.

Registration includes coffee- and lunch breaks.

AGENDA

The use-cases within the workshops will be based on published examples.

We will develop PBPK models for small molecules (DDI and pediatric populations) biologics (antibody-drug conjugates (ADCs)). We will then develop a more advanced PB-QSP model for treatment of tumor growth (& modeling of growth inhibition).

The two workshop days are scheduled as follows:

Day 1

Agenda Day 1

Day 2

Agenda Day 2

PREPARATION

  • BRING YOUR LAPTOPS, pre-installed with the software! We will be doing hands-on work!

  • To download the software, please click here

  • Download & install the R distribution (Ver 3.5+) from here

  • Download & install FREE RStudio Desktop (a GUI for R with additional functionalities for e.g. debugging and code visualization) from here

  • For starters, please check out the tutorial site (videos & hands-on) here

NOTES

  • Please add this site to your watchlist (very top of page) to be informed of any changes.

Visit our News & Events section for info on upcoming workshops and our future developments in physiologically-based quantitative-systems-pharmacology.



Best Regards,

Stephan Schaller
(Managing Director, esqLABS GmbH)

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Date and Time

Location

QSPC2020

See Text Description

Leiden

Netherlands

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Refund Policy

Refunds up to 7 days before event

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