$50 – $10,000

Penn Orthopaedics 2017 Cartilage Repair Symposium

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Smilow Center for Translational Research

Rubenstein Auditorium

3400 Civic Center Boulevard

Philadelphia, PA 19104

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Join us for a Clinical and Scientific Gathering Focused on the Cutting Edge of Cartilage Repair:

Advances in Biological Joint Replacement

Featuring Keynote Speakers:

Daniël Saris, M.D., Ph.D., Utrecht University (The Netherlands)

Farshid Guilak, Ph.D., Washington University (St. Louis, MO)

Target Audience: The symposium attracts orthopaedic surgeons, non-operative sports medicine physicians, physical therapists, athletic trainers, nurses, and physician assistants to learn about the latest techniques in cartilage repair. With a focus on basic science, we also attract the best scientists and engineers to present their cutting edge work. In addition, we will be offering free admission for up to two (2) residents from the Orthopaedic Surgery programs at each of the major medical centers in the region.

Statement of Need: The symposium will include invited talks by key thought leaders in the field of cartilage biology, biomaterials, stem cells, tissue engineering, animal models, and imaging, as well as clinical methods for the treatment of cartilage damage in the knee. Speakers will also discuss rehabilitative protocols that promote successful recovery.

Attendees will have the opportunity to engage in hands on training in the most advanced repair techniques in the Human Tissue Laboratory at the University of Pennsylvania. The intent of this meeting is to build consensus, informed by clinical practice and basic and translational research, to define new directions in the field that will drive the treatment of cartilage injuries in the knee from the current status of repair towards the promise of regeneration.

Course Directors:

James L. Carey, M.D., MPH, Director of the Penn Center for Advanced Cartilage Repair and Osteochondritis Dissecans Treatment, Assistant Professor of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania

Robert L. Mauck, Ph.D., Associate Director for Research, Penn Center for Advanced Cartilage Repair and Osteochondritis Dissecans Treatment, Mary Black Ralston Professor of Orthopaedic Surgery, Professor of Bioengineering, Perelman School of Medicine at the University of Pennsylvania

Course Planning Committee:

Brian Eckenrode, PT, DPT, OCS, Assistant Professor of Physical Therapy at Arcadia University, Coordinator of the Arcadia University Orthopaedic Clinical Residency, Director of the Arcadia University Running Injury Clinic

Miltiadis H. Zgonis, M.D., Co-Director, Human Tissue Laboratory, Assistant Professor of Orthopaedic Surgery at the Hospital of the University of Pennsylvania

George R Dodge, Ph.D., Associate Professor of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, Co-Director, Translational Musculoskeletal Research Center, Philadelphia VA Medical Center

Kyla Ortved, DVM, PhD, DACVS, DACVSMR, Assistant Professor of Large Animal Surgery University of Pennsylvania


Friday – April 28, 2017

1:30 PM – 2:30 PM: Registration at Smilow Center for Translational Research

2:30 PM – 2:40 PM: Welcoming Remarks
James L. Carey, M.D., M.P.H.
Robert L. Mauck, Ph.D.

Moderator: George R. Dodge, Ph.D.

2:40 PM – 3:10 PM: An Engineering Perspective on Biologic Joint Replacement
Farshid Guilak, Ph.D.

3:10 PM – 3:20 PM: Discussion; Q & A

3:20 PM – 3:35 PM: Joint Lubrication
David Burris, Ph.D.

3:35 PM – 3:50 PM: Role of Small Proteoglycan in Cartilage Function and Osteoarthritis
Lin Han, Ph.D.

3:50 PM – 4:05 PM: Cellular Origins and Patterning of Regenerated Lizard Tail Cartilage
Thomas P. Lozito, Ph.D.

4:05 PM – 4:20 PM: Discussion; Q & A

4:20 PM – 4:40 PM: Afternoon Break, Review of Posters and Exhibits

Moderator: Kyla Ortved, DVM, PhD, DACVS, DACVSMR

4:40 PM – 5:10 PM: A Clinical Perspective on Biologic Joint Replacement
Daniël Saris, M.D., Ph.D.

5:10 PM – 5:20 PM: Discussion; Q & A

5:20 PM – 5:35 PM: Novel Biologics for Whole Joint Restoration
George R. Dodge, Ph.D.

5:35 PM – 5:50 PM: Anatomical and Morphological Considerations for Whole Joint Regeneration
Matthew Fisher, Ph.D.

5:50 PM – 6:05 PM: Mechanical Considerations for Whole Joint Regeneration
Suzanne Maher, Ph.D.

6:05 PM – 6:20 PM: Discussion; Q & A

6:30 PM – 7:30 PM: Poster Review and Exhibitor Cocktail Hour at Smilow Center for Translational Research

8:00 PM – 9:30 PM: Faculty Dinner (Invitation only)

Saturday – April 29, 2017

7:30 AM – 8:30 AM: Registration and Breakfast

Moderator: Brian J. Sennett, M.D.

8:30 AM – 8:45 AM: Meniscal Transplantation and Other Concomitant Soft Tissue Reconstruction
Nicole S. Belkin, M.D.

8:45 AM – 9:00 AM: Assessing Alignment and Correcting Malalignment

9:00 AM – 9:15 AM: Sex Differences in Cartilage Injury and Repair
Ellen K. Casey, M.D.

9:15 AM – 9:30 AM: Discussion; Q & A

Moderator: Bob Spiro, Ph.D.

9:30 AM – 10:00 AM: SUMMIT Trial – MACI Experience in Europe
Daniël Saris, M.D., Ph.D.

10:00 AM – 10:15 AM: Discussion; Q & A

10:15 AM – 10:45 AM: Morning Break

Moderator: Marisa Pontillo, Ph.D., D.P.T., S.C.S.

10:45 AM – 11:00 AM: Accelerated Rehabilitation Following Cartilage Repair
Brian J. Eckenrode, D.P.T., O.C.S.

11:00 AM – 11:15 AM: Return to Sport Considerations Following Cartilage Surgery
Elliot Greenberg, D.P.T., O.C.S.

11:15 AM – 11:30 AM: Systematic Review of New Cartilage Repair Techniques
Vishal Saxena, M.D.

11:30 AM – 11:45 AM: Discussion; Q & A

11:45 PM – 12:00 PM: Perspectives on Challenges Ahead and Concluding Remarks
James L. Carey, M.D., M.P.H.
Robert L. Mauck, Ph.D.

12:00 PM: Adjourn

Conference participants that are registered for Human Tissue Laboratory module will walk to laboratory and change into proper attire by 2:00PM.

Moderator: Miltiadis H. Zgonis, M.D.

Please note: All conference participants that are registered for this portion will have an opportunity to practice these skills on a cadaver at their station.

All conference faculty will act as instructors at a station.

2:00 PM – 3:00 PM: Autologous Chondrocyte Implantation (including MACI, NOVOCART, and CartiONE)
Daniël Saris, M.D., Ph.D.
James L. Carey, M.D., M.P.H.

3:00 PM – 4:00 PM: Meniscus Transplantation
Brian J. Sennett, M.D.
Dinesh Dhanaraj, M.D., M.S.P.H.

4:00 PM – 5:00 PM: Alignment Correction
To be Announced
Nicole S. Belkin, M.D.

Athletic Trainers: Scientific and Lab sessions: The University of Pennsylvania Health System is recognized by the Board of Certification, Inc. to offer continuing education for Certified Athletic Trainers. This program has been approved for a maximum of (XX) hours of Category A continuing education. This continuing education course is considered to be an Advanced Level program. Certified Athletic Trainers are responsible for claiming only those hours actually spent participating in the continuing education activity. BOC Approved Provider Number: P8102

Physical Therapists: An application has been submitted to the Pennsylvania State Board of Physical Therapy for approval of physical therapy contact hours to be awarded to physical therapists attending this conference. Approval is pending.

We are not offering CME at this conference.

An unconditional educational grant to support the Penn Cartilage Symposium provided by









Penn Relays - Please note that registered guests can purchase a Penn Relay ticket - see additional options at end of registration page for cost. Visit the Penn Relay website to learn more. http://thepennrelays.com

Become a Sponsor - Please see our full details including new sponsor levels BY CLICKING HERE. This symposium is a great way to promote your brand and provide opportunities for your representatives to network with our attendees.

To arrange for your sponsorship benefits or if you have any questions, please contact our Conference Manager, Lauren Huezo at Albrecht Events at (215) 801.5242 or PCRS@albrechtevents.com

Hotels - A room block has been secured at the following center city hotel. Please note that due to the Penn Relays hotel rooms are limited so please book early. These discounted rates are only vaid until March 27, 2017 or until room block is full.

Hotel Palomar Philadelphia - Click here for rates and to book a room

Parking: The symposium will be at the Smilow Center for Translational Research at 3400 Civic Center Boulevard in Philadelphia, Pennsylvania. The building is physically integrated and shares the same 3400 entrance with Penn's Perelman Center for Advanced Medicine and Roberts Proton Therapy Center.

Due to the Penn Relays University City will be busy and parking will be limited. For both days please park in the 3600 Civic Center Boulevard Garage and NOT at the Perelman Center for Advanced Medicine. The parking rate at the 3600 Garage is $20.00 daily.

Please see this link for directions, more parking details and public transportation options: PARKING LINK


In order to process refunds for course withdrawals, cancellations must be received via email by Friday, April 7, 2017 (subject to a service charge equivalent to 10% of the registration fee). No refunds will be issued thereafter.

The University reserves the right to cancel or postpone any course due to unforeseen circumstances. In the event of cancellation or postponement, the University will refund any registration fees but is not responsible for any related costs or expenses to participants, including cancellation fees assessed by hotels, airlines, and travel agencies.

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Smilow Center for Translational Research

Rubenstein Auditorium

3400 Civic Center Boulevard

Philadelphia, PA 19104

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