Novel Molecular Targets in Mood Disorder and Psychosis: A Workshop
Event Information
About this Event
Summary
The National Academy of Science Engineering and Medicine's Forum for Neuroscience and Nervous System Disorders is hosting a 1.5 day long virtual conference on Novel Molecular Targets in Mood Disorders and Psychosis on March 8-9, 2021. To watch the webcast, visit the workshop homepage here and scroll to the video player.
March 8, 2021: 2:00pm-5:00pm ET
March 9, 2021: 10:00am-5:00pm ET
Background
For many individuals living with mental illness, current pharmacological interventions fail to deliver adequate relief. However, recent advances in our understanding of the mechanisms of action underlying psychiatric disease have led to the identification of new classes of molecular targets for drug development. A handful of new and emerging compounds that act on these novel molecular pathways have shown promising results in clinical trials for the treatment of depression and other mental illnesses, including ketamine and other NMDA receptor antagonists, GABA receptor modulators, muscarinic antagonists, and serotonergic agonists. These findings have re-energized scientific research into new opportunities for targeted drug development in this field, but many open questions remain.
What are commonalities among the new mechanisms of action being discovered? How can lessons learned in translation and clinical development be applied across drug development programs? What are approaches to addressing key clinical and ethical questions relating to prescribing, dosing, regulation, and minimization of abuse potential?
This virtual public workshop will bring together experts and key stakeholders from academia, government, industry, and non-profit organizations to explore these and other related questions relevant to advancing novel molecular targets in the neuropharmacology of mood disorders and psychosis.
Meeting Materials
Planning committee member biosketches
For additional supplementary materials, visit the workshop homepage here.
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