Date: September 24, 2013
Time: 1:00 p.m. to 5:00 p.m.
Location: FDA White Oak Campus
10903 New Hampshire Ave.
Building 31, Room 1503A (Great Room)
Silver Spring, MD 20993
On September 24, 2013, FDA is conducting a public meeting on Narcolepsy Patient-Focused Drug Development. FDA is interested in obtaining patient input on the impact of narcolepsy on daily life (topic 1) and currently available therapies to treat the condition (topic 2). The questions for discussion on these topics are located at the bottom of this page.
For each of these topics, a panel of patients and patient representatives/advocates will present comments to begin the dialogue and will be followed by a facilitated discussion inviting comments from other patients and patient representatives.
If you are interested in providing comments as part of the initial panel discussion, indicate so during the registration process. Participants for the panel discussions will be confirmed prior to the meeting.
There will also be an opportunity for patients, patient representatives and others to provide comments on issues other than topics 1 and 2 during an Open Public Comment session. Sign up for Open Public Comment will take place the day of the meeting.
For more information, refer to the FDA meeting website at http://www.fda.gov/ForIndustry/UserFees/PrescriptionDrugUserFee/ucm359018.htm.
Questions for Discussion
Topic 1: Disease symptoms and daily impacts that matter most to patients
1) Of all the symptoms that you experience because of your condition, which 1-3 symptoms have the most significant impact on your life? (Examples may include excessive daytime sleepiness, cataplexy, etc.)
2) Are there specific activities that are important to you but that you cannot do at all, or as fully as you would like, because of your condition? (Examples of activities may include sleeping through the night, work and school performance, etc.)
3) How have your symptoms changed over time?
a) Do your symptoms come and go? If so, do you know of anything that makes your symptoms better? Worse?
Topic 2: Patients’ perspectives on current approaches to treating narcolepsy
1) What are you currently doing to help treat your condition or its symptoms? (Examples may include FDA-approved medicines, over-the-counter products, and other therapies including non-drug therapies such as lifestyle modifications.)
a) What specific symptoms do your therapies address?
b) How has your treatment regimen changed over time, and why?
2) How well does your current treatment regimen treat the most significant symptoms of your disease?
a) How well do these therapies improve your ability to do specific activities that are important to you in your daily life?
b) How well have these therapies worked for you as your condition has changed over time?
3) What are the most significant downsides to your current therapies, and how do they affect your daily life? (Examples of downsides may include bothersome side effects, inconvenient dosing schedules, access issues, etc.)
4) Assuming there is no complete cure for your condition, what specific things would you look for in an ideal therapy for your condition?