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LRIG-Philadelphia Virtual Scientific Meeting Jan 2021

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LRIG-Philadelphia's Virtual Scientific Meetings provide an opportunity for Scientists to share their research with the LRIG Community.

About this Event

The Laboratory Research & Innovation Group of Philadelphia (LRIG-Philadelphia) is proud to present another Virtual Scientific Meeting. This lunch time "WebEx" event will feature a presentation by a scientist from GlaxoSmithKline (GSK) and an opportunity for questions and answers.

Overview of Presentation:

Automated Platform Analytical Method to Determine Excipient Content in Biopharmaceutical Drug Product using Andrew Alliance Liquid Handler Robot

The Andrew Alliance liquid handler robot enables automated pipetting, flexible programmable settings, and simple drag and drop protocol designs. This talk describes the automation development challenges and solutions to fully automate a platform analytical method to determine excipient content in monoclonal antibody (mAb) biopharmaceutical drug product.

Please remember to register and join us for this exciting virtual event. The evening before the event you will receive a link that will allow you to join the WebEx meeting.

See below for Information on our speaker and an abstract of her presentation.

Sharon Matamoros

“Sharon Matamoros is a Analytical Automation Specialist in the small molecule High-Throughput Automation Group at the GSK Collegeville site. She has been a member of the team since 2018 and focuses on applying automation to accelerate early-phase drug development. She has a background in Analytical Chemistry”.

LinkedIn: https://www.linkedin.com/in/sharon-matamoros-0a600027/

Automated Platform Analytical Method to Determine Excipient Content in Biopharmaceutical Drug Product using Andrew Alliance Liquid Handler Robot

Sharon Matamoros, GlaxoSmithKline, 1250 South Collegeville Rd, Collegeville, PA 19426

Abstract : The implementation of laboratory automation can accelerate the chemistry, manufacturing, and control activities and build quality into the process. The Andrew Alliance liquid handler robot enables automated pipetting, flexible programmable settings, and simple drag and drop protocol designs. This liquid handler robot is user friendly and ideal for Scientists with limited robotics knowledge. This talk describes the automation development challenges and solutions to fully automate a platform analytical method to determine excipient content in monoclonal antibody (mAb) biopharmaceutical drug product. The automation accomplishes standard solution preparations for a calibration curve, samples with a variety of viscosities, and analytical controls. Analyst vs robot performance is discussed including linearity, precision and accuracy of the results. Automation was successfully implemented in a new laboratory to execute a robust sample preparation protocol.

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