$150 – $1,500

Introduction to PBPK modeling in R with mrgsolve

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CIC Cambridge - Main Street

101 Main Street

Cambridge, MA 02142

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This 1.5 day hands-on workshop will provide participants with a technical foundation for physiologically-based pharmacokinetic (PBPK) model development in R using mrgsolve, a free, open-source modeling and simulation platform for ODE-based model development in R (https://mrgsolve.github.io). The workshop gets started with an introduction to simulation with mrgsolve. We'll cover the essentials of a tidy simulation workflow in R. Then we'll jump into PBPK modeling with mrgsolve. After a brief introduction to principles of PBPK, we'll work through case studies using PBPK modeling. The case studies use published models focused on problems like drug-drug interactions and exploring pharmacokinetics in special populations. Finally, we will introduce tools and workflows in R to help you accomplish modeling tasks such as sensitivity analysis and parameter estimation.

Wednesday June 6, 2018 from 1:00pm-5:30pm
Thursday June 7, 2018 from 9:00am to 5:00pm

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Location

CIC Cambridge - Main Street

101 Main Street

Cambridge, MA 02142

View Map

Refund Policy

Refunds up to 7 days before event

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