€64.42 – €740.22

In Vitro Tools for Assessing EDC

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Amsterdam

Science Park 406

1098 Amsterdam

Netherlands

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Description

Final agenda and practical information are available here.

You will learn in a 2 day extensive hands-on training how you can use a panel of standardized stable human- and yeast reporter cell lines for rapid screening of hazards of pure chemicals and complex mixtures on multiple adverse outcome pathways (BioDetection Systems & BASF). This includes those pathways prioritized in the current regulatory context of EDC assessment, including interference with estrogen-, androgen-, and thyroid hormone signaling. This will include assessment of metabolic conversions (S9, metabolically competent liver cells - BIOPREDIC ) of EDCs using various approaches and assessment of their effects on steroidogenesis.

Furthermore, the participants will integrate in silico read-across predictions (TNO) that can be particularly suited to confirm biological assays and vice-versa. Moreover, they will be presented information on QSAR models and their performance for a number of ED-related endpoints (DTU).Trainees will learn more about modern robotic and automated high throughput screening using down-scaled 96-wells to 384-wells formats. The chemical activated luciferase (CALUX) assays are available for testing of relevant matrices such as food, blood, urine, mother milk and many different environmental matrices. All steps needed from extraction, clean-up, cell culture handling, luminometer analysis and calculations of effect concentrations and toxic equivalents will be presented in state-of-the-art manner following current guidelines (e.g. ISO 17025, OECD TG455-like, ISO 19040-3).

Additionally a state-of-the-art open keynote will be presented by Elise Grignard (European Commission, JRC) along with several oral presentations on the current applications in chemicals, mixture toxicity, food, environmental and public health testing.

More topics for 2017 are available under the organizer name CAAT Academy


If you wish to advertise during this session, please send an email to caat-academy@uni-konstanz.de


FAQs

What's the refund and cancellation policy?

Refunds are available only if BDS or CAAT Academy cancels the event. This is stated on the participant’s receipt once registered. However, tickets may be transferable if the ticket holder is unable to attend the event. In principle the ticket may only be transferred within the same price category but a final decision will be made at CAAT Academy's discretion.

Do I actually manipulate in the lab?

Each hands-on training is scheduled to last for 2-Days. In these two days, the hands-on trainings encompass 20% Lectures and 80% Laboratory practices. In other words, for about more than a day and a half of the trainings each participant will able to actively manipulate in the laboratory in small groups of 3-4 people. Therefore, some preliminary knowledge for cell culture in the lab is mandatory.

What is the difference between “private” sector and “non-private” sector?

The participant must choose the "private” sector in case his/her organization has any commercial activities e.g. selling products or services to third parties.

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Date and Time

Location

Amsterdam

Science Park 406

1098 Amsterdam

Netherlands

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