IMO Workshop 6: Resistance
Welcome to the registration page for the 6th Integrated Mathematical Oncology (IMO) workshop at the Moffitt Cancer Center. Now in its 6th year we are excited to announce that the Moffitt Physical Sciences Oncology Center (Moffitt PSOC) is fully sponsoring our event. The Moffitt PSOC is part of the Physical Sciences Oncology Network (PS-ON) supported by the National Cancer Institute (NCI). The IMO workshop is designed to motivate and facilitate a hands-on modeling experience focused on treatment resistance in cancer. The workshop is comprised of both an educational event and competition and divides participants into multiple teams combining clinical, experimental and theoretical members. These teams integrate their energies to develop and implement a mathematical model focussed on treatment resistance in cancer. The teams are expected to come up with a model, solve it and give a presentation all within 4.5 intense days.
As always we will have several independent judges to view both the specific aims and the closing presentations to decide the winning team. To facilitate integration and motivate participation we are offering an Amazon gift voucher to active participants of the winning team and to the runner up team. In addition, to facilitate further development of the winning project we are offering a $50K pilot grant to the leaders of the winning team.
As with last years workshop there will be a "speed dating for scientists" to break the ice among diverse group of participants on the 6th. The opening presentation on the 7th will summarise what is expected of the teams and serve to motivate the subsequent hands on model development sessions. For the 1st time we plan to have an seperate poster session on the evening of the 7th to allow participants to showcase their own research. Participation in the workshop requires registration in order to generate the teams and give numbers for the food and beverages we are providing throughout the workshop.
We are offering deluxe travel awards for external participation!!! Each award will cover flight + accommodation + per diem for up to 6 nights and allow for both national and international scientists to participate in this unique hands on educational event. If you are either a PhD student, Postdoctoral student or junioir faculty with a passion for research and a desire to better understand cancer resistance as well as how to build integrated models then please apply during the registration process. Please note: the travel awards are extremely limited and will be offered on a competitive basis, application does not gaurantee participation. If you are able to cover your own expenses, please indicate this during the registration process.
TRAVEL AWARD APPLICATIONS WILL BE CLOSING ON FRIDAY 7th of October 2016 at Noon EST. AWARD WINNERS WILL BE CONTACTED after 10th October 2016.
Drug resistance is currently the single biggest issue in cancer today. Despite the development of a new generation of molecularly targeted drugs, which showed initial promise, resistance remains the key driver of treatment failure. This is largely due to the heterogeneous nature of cancer, this heteogeneity bridges many scales: genetic, epigeneitc, phenotypic, microenvironmental and seen both within (itra-tumour) and across patients. Developing treatments that do not ignore this heterogeneity and instead exploit it, has become part of an emerging paradigmn of evolutionary enlightened therapies. However, treating cancer like a chronic disease means that we need a better understanding of the disease kinetics (both with and without drug). Mathematical models are an ideal tool for understanding how heterogenous cancers respond to therapy and can suggest smart strategies to maximize response whilst minimizing both resistance and toxicity. This workshop will consider all aspects of drug resistance through a range of cancers and treatments. More explicit details will follow.
Sunday, 6PM, 6th November 2016 - Friday 1PM, 11th November 2016.
Speed dating & Poster session: SRB Atrium, 6PM 6th November.
Intoductory presentation: SRB Murphey, 9AM 7th November.
Working group sessions: Various rooms, 7-10th November.
Closing presentations: SRB Murphey, 9AM 11th November.
Chair and contact
The IMO Workshop is chaired and organized by the IMO Department Chair, Sandy Anderson. For more information concerning participation or about the workshop in general please contact IMO Department Asisstant Yvette Mieles directly at Yvette Mieles@Moffitt.org.
Moffitt Cancer Center
12902 Magnolia Drive
Stabile Research Building
Moffitt Cancer Center, Integrated Mathematical Oncology
The primary goal of Integrated Mathematical Oncology Department, at the Moffitt Cancer Center, is the integration of theoretical and computational modeling tools into clinical and experimental cancer research to aid in both the core understanding of cancer processes and the mechanisms that drive them.
By using a range of mathematical modeling approaches targeted at specific types of cancer we will aid in the development and testing of treatment strategies. This multi-model, multi-scale approach allows for a diverse and rich interdisciplinary environment that will create many novel approaches for the treatment and understanding cancer.