$799 – $1,700

CPD Accredited World Congress on Glycobiology (AAC)

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Bangkapi Krung Thep Maha Nakhon, Bangkok 10310

Thailand

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CPD AccreditedWorld Congress on Glycobiology

About Conference
It is a great pleasure and an honour to extend our warm invitation to attend the “World Congress on Glycobiology”. Glycobiology Congress 2019 will be held in Bangkok, Thailand during September 2-3, 2019.
The benefits of this large-scale collaborative meeting include broader content areas, efficiency in meeting attendance and costs for delegates and trade partners, a more diverse variety of sessions, and increased attendees. Our scientific program includes invited Plenary presentations, Symposia and Seminars, Meet-the-professor sessions, basic and clinical abstract presentations, young investigator awards, and interactive poster sessions.

Why to Attend?
The meeting will provide many opportunities to network and discuss with members from around the world focused on learning about Biological research and growing market, this is your single best opportunity to reach the largest assemblage of participants from the scientific community. Conduct demonstrations, distribute information, meet with current and potential customers, and make a splash with a new product line, and receive name recognition at this 2-day event. World-renowned speakers, the most recent techniques, tactics, and the newest updates in Glycobiology growing market are hallmarks of this conference.

Target Audience:
Post-Doctoral Fellows
Research and Diagnostic Laboratories
Directors/Managers & Business Delegates
Director of Laboratories
Universities
Industries
Investigators
Clinical Fellows
Students and Biomedical Research Companies.

Sessions/Tracks
Glycobiology and Glycochemistry

It study of everything related to the structure, bio-synthesis and biology of sugars and saccharides drawing from simple organic chemistry, molecular and cellular biology, enzymology and allied domains. Sugars management and influence nearly each facet of the cellular processes starting from cell-cell interactions, energy intermediates, adhesion mechanisms, growth factor signaling, blood clotting, receptor binding, regulating the activity of hormones within the blood, guiding embryonic development, and serving structural roles. In this new light-weight, the role of sugars is being reconsidered with a brand new zeal to grasp the operating of the convoluted processes of life.

Molecular Glycoscience and Monosaccharides

Glycoscience has become a significant, increasing and necessary extension of contemporary biological science and biomedicine in today’s era. The wider complexness of glycosylated and connected structures is merely paralleled to their utility. Discovering saccharide and glycan antigens as cancer biomarkers or perhaps abnormal glycation pathways in metabolic disorders like polygenic disorder reserved the importance of the enlargement of glycoscience during a future, as the simplest way of representing new biomarkers and therapeutic targets in illness. The final goal is to enhance research capabilities on glycosciences and provide ground to present and future emerging discoveries in glycosciences into new clinical applications and diagnostics.

Proteoglycan and Sialic acid

Proteoglycans are more than 95% carbohydrate by weight. Proteoglycan helps to supply U.S.A. with the thought to the molecule's numerous chemical compositions. As proteo refers to the protein, while glycan represents sugar or a group of sugars, so proteoglycan is a long polysaccharide chain covalently attached to a protein. The supermolecule element of proteoglycans is synthesized by ribosomes and primarily translocated into the lumen of the rough endoplasmic reticulum. Sialic acid may be a generic term for the N- or O-substituted derivatives of neuraminic acid, a sugar with a nine-carbon backbone and square measure found cosmopolitan in animal tissues and to a lesser extent in another organisms, starting from fungi, plants, yeasts and bacterium, largely in glycoproteins and gangliosides.

Glycoproteomics Analysis

Glycoproteomics is emerging and booming as an important sub-discipline of proteomics, focusing on the role of protein glycosylation in various biological processes. It focusses on the branch of genetics that identifies, summarizes, and characterizes proteins containing carbohydrates as a post-translational modification by using Mass spectrometry which is commonly and widely used to identify the sugar moieties attached. Glycomics is the comprehensive study of glycomes the entire complement of sugars, whether free or present in more complex molecules of an organism including genetic, pathologic, physiologic, and other aspects. Glycomics "is the systematic study of all glycan structures of a given cell kind or organism" and may be a set of glycobiology.

Protein engineering and Glycoimmunology

Carbohydrates were important within the early history of medicine in describing the identity of antigens that area unit recognized by antibodies. So the ability of those antibodies to unambiguously acknowledge glycans and carbohydrate-related molecules was exploited in studies process the dimensions of the antigen-binding website. Numerous carbohydrate-binding proteins or lectins are known on the surfaces of immune cells that intensify the importance of carbohydrates in each innate and adjustive immune responses within the development of modern vaccines and immunological therapeutics. Recently glycobiologists and immunologists area unit currently collaborating extensively to explore this significant field within the space of immunobiology.

Glycolipids and Glycopeptides

Glycolipids area unit restricted in fractions however glorious to be major and necessary contributors to glycoconjugates all told areas of life. The structural diversity of glycolipids is outstanding, as differing kinds of lipids area unit glycosylated in nearly each kinds of life like animals, plants, and microorganism. Their role primarily is to keep up the steadiness of the membrane and to facilitate alternative cellular recognition. They act as glycan-carriers within the membranes of photosynthetic structures in, algae, plants, and microorganism. Glycopeptides area unit primarily amides that contain sugar moieties usually glycan’s that area unit covalently hooked up to the facet chains of the organic compound residues that represent the peptide. These embrace a category of medication of microbic origin that area unit composed of glycosylated cyclic or polycyclic non-ribosomal peptides.

Glycopathology: Glycans in Cancer

Carbohydrates are essentially thought-about as major sources of structural materials and energy for living organisms. Recent research’s during this space has centered in the main on easy basic sugars and homopolysaccharides like starch, cellulose, glycogen, and chitin. During the previous few decades, the researchers have shifted their concentrate on advanced forms like carbohydrates, particularly proteoglycans, glycolipids and glycoproteins that are jointly cited as glycoconjugates that shows the potential of recognition markers within the biological system that additionally relates to alternative medical specialty and clinical fields. The roles of glycans and glycoconjugates are stressed as a result of a tiny low alteration in glycosylation can staggeringly regulate the total pathway and mechanisms of cancer, that leads to a sign as a biomarker development resulting in varied medical specialty development in cancer analysis.

Glyconeurobiology: Glycans in Neuroscience

Carbohydrate-rich molecules like as well as glycolipids, glycoproteins and proteoglycans within the system have vital roles throughout development, regeneration and colligation physical property. The structural diversity of the macromolecule moieties renders them ideally suited as stage-specific biomarkers for numerous cell varieties resulting in mediate interactions between recognition molecules, thereby contributive to the formation of a posh molecular framework at the cell surface and within the living thing matrix of the cell. The exceptional structural diversity of glycan chains and connected moieties permits for huge advanced prospects that may result in cell interactions together with cell-matrix interactions.

Glycoconjugates and Glycomics and Metabolomics

Glycomics parallel to genetics and genetic science is that the systematic study of all the glycan structures of a given cell sort or organism and may be a set of glycobiology. Sugars are usually connected to alternative varieties of the biological molecule to create glycoconjugates. The various catalyst method of glycosylation creates sugars or saccharides connected to themselves and to alternative molecules by the glycosidic bond, finally manufacturing glycans. Proteoglycans, glycoproteins, and glycolipids ar the foremost extensive glycoconjugates found in class cells. Glycoconjugates are shown to be vital and play a outstanding role in cell-cell interactions thanks to the presence on the cell surface of assorted glycan binding receptors in addition to the glycoconjugates themselves.

Mass Spectrometry in Glycobiology Research

Mass spectroscopic analysis (MS) may be a important analytical technique that ionizes chemical species and kinds the ions supported their mass-to-charge magnitude relation. A spectrum may be a plot of the particle signal as a perform of the mass-to-charge magnitude relation throughout experimental analysis. These spectra are then used to determine the elemental or isotopic signature of a sample for observations, the masses of particles and of various molecules and to clarify the chemical structures of desired molecules like biomolecules, glycopeptides and different chemical compounds.

Glycans in Vaccine Development

Recent technological advances within the field of glycobiology and glycochemistry square measure showing the manner for a brand new era in macromolecule connected immunogen style. This is sanctionative an incredible potency within the synthesis, identification, and analysis of distinctive glycan epitopes found on variety of pathogens and cancerous cells. Glycans and connected macromolecule molecules square measure at the middle of the many disorders and diseases gap the chance of exploiting them for therapeutic and diagnostic functions. There square measure numerous organic chemistry pathways and diseases during which carbohydrates square measure complexly concerned.

Glycans in Diseases and Therapeutics

Glyco-epitope diversity enhances the role of glycan’s and is now considered essential for life, both under normal and pathological conditions. The very important role of glycans within the analysis and development of diseases and therefore the potential therapeutic use of this category of molecules by describing however the interaction of glycans with growth factors, extracellular proteases, growth factor binding proteins, protease inhibitors, chemokine’s, morphogens, and adhesive proteins regulates inflammation, infection, atherosclerosis, cancer, thrombosis, and embryonic stem cell biology.

Lipid and Lipoprotein Metabolism

Hyperlipoproteinemia is that the supermolecule unsettling influence of great relevance clinically as a results of its link with AN enlarged danger of arterial sclerosis vas illness. Since lipids don't seem to be solvent in blood, they're transported as lipoproteins when response with water-dissolvable proteins within the blood. Lipids within the blood area unit consumed by liver cells to relinquish vitality to cell capacities. Overabundance lipids within the blood area unit within the long haul modified over into fat tissue. Unusually elevated amounts of triglycerides and steroid alcohol area unit presupposed to be concerned in curing of the corridors.

Protein-Lipid & Lipid-Lipid Interactions

An individual lipoid particle can keep within the circular shell around a macromolecule for simply a quick timeframe. Tying to the circular shell indicates usually lowest auxiliary specificity. And the annular lipid, there is proof for other lipid atoms bound between the transmembrane alpha-helices of the protein; these lipids are alluded to as non-annular lipids. Voltage-gated channels square measure key transducers of film potential changes into living thing homeless folks that begin various physiological occasions. The conformational modification mutilates the state of the channel proteins adequately specified the Great Depression, or channel, opens to concede particle flood or effluence to happen over the layer, down its electrochemical angle.

Lipids in Molecular Medicine and Virology

Clinical medication that connect with membrane lipids which modify the composition and structure of cell membranes will remodel the localization and/or activity of membrane proteins. In general, changes in membrane macromolecule structure square measure emulated in changes in membrane macromolecule activity. Several medication accustomed fight against cancer, vessel diseases and blubber and different pathologies, confirm macromolecule structure within the semipermeable membrane and that they manufacture a concomitant alteration within the localization and activity of signaling proteins. The recent studies have resulted in characteristic specific disease-provoking factor mutations and have light-emitting diode to improved clinical and laboratory treatments, diagnostic procedure in lipid-related diseases.

Lipids in Signaling and Intracellular Trafficking

Understanding the mechanisms of animate thing trafficking and its interaction with different signal molecules could result in novel approaches within the treatment of variety of hematological and different diseases. NIH has invested with $127,980 during this specific space in 2015. Lipid rafts are vessel like structures are made in proteins and to boot lipids, as an example cholesterin and sphingolipids and have a number of capacities in signal transduction. They assume a vicinity in sickness cells advancement, endocytosis and therefore the uptake of morbific microorganisms and sure infections. Ponders that have illustrated the a part of lipoid pontoons in drooping by means that of bioreceptor amino acid kinases and G protein-coupled receptors. The vitamin B complex phospholipids frame the essential premise for a impressive interchange of drooping reactions created, most often, by receptor feat and delivery concerning changes in Ca+2, macromolecule enzyme falls and particle channel/exchanger movement. Phosphatidylinositol (PI) itself could be a negligible lipoid constituent of all eucaryote plasma films.

Glycoengineering

Glycans area unit at the middle of the many disorders and diseases sparking the chance of exploiting them for therapeutic and diagnostic functions. There are many biochemical pathways and diseases in which glycans are intricately involved. Gaging the vast potential and the promise that glycobiology holds many pharma and biotech companies have already started allocating their R&D budget to it. Presently, with our drug arsenal quick depleting against drug resistant and mutant pathogens, glycobiology hold AN untapped supply of latest candidate medicine.

Genomics and Metabolomics

Genomics is that the study of the order as critical biological science that alludes to the investigation of qualities and their components in bequest. Genomics may be viewed as a train in hereditary qualities. It applies DNA, desoxyribonucleic acid sequencing ways and bioinformatics apparatuses to grouping, gather and break down the capability and structure of genomes with the overall arrangement of desoxyribonucleic acid within a solitary cell of a creature. The field endeavors to choose the entire deoxyribonucleic acid grouping of creatures and fine-scale hereditary mapping.

AGENDA

Please contact the event manager Marilyn (marilyn.b.turner(at)nyeventslist.com ) below for:
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- Event sponsorship

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Bangkapi Krung Thep Maha Nakhon, Bangkok 10310

Thailand

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