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Cortical Connections Conference 2019

Intn'l Research Consortium for the Corpus Callosum & Cerebral Connectivity

Thursday, June 13, 2019 at 8:45 AM - Friday, June 14, 2019 at 5:30 PM (CEST)

Cortical Connections Conference 2019

Ticket Information

Ticket Type Remaining Sales End Price Fee Quantity
Cortical Connections Conference 2019; General Admission   more info 67 Tickets May 15, 2019 €100.00 €6.49
Cortical Connections Conference 2019; Student   more info 18 Tickets May 15, 2019 €35.00 €2.92
Cortical Connections Conference 2019; Family 15 Tickets Jun 13, 2019 €50.00 €3.74

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Event Details

The Cortical Connections Conference is a scientific meeting about developmental anomalies of cortical connectivity (specifically the corpus callosum). Conference speakers include scientists and clinicians from around the world; leading experts from the fields of developmental neuroscience, laboratory genetics, clinical genetics, paediatric neurology, neuroimaging and neuropsychology. 

The program consists of a series of brief presentations arranged in general progression from cellular & molecular studies, to neural diagnostics in humans, and finally to higher-level cognitive and behavioral issues related to anomalies of cortical connectivity. 

Registration closes when 180 people register or on May 15 (whichever comes first).

Registration must be completed online in Eventbrite, including payment of a 100 € per person for professionals and 35 € per person for students.


La conférence sur les connections corticales est une réunion scientifique sur les anomalies du développement de la coonectivité corticale et spécifiquement du corps calleux. Les intervenants sont des scientifiques et des cliniciens venant du monde entier : des experts en neuroscience développementale, génétique, neuropédiatrie, imagerie cérébrale, et neuropsychologie.

Le programme consiste en une série de présentations organisées de manière progressive : des études moléculaires et cellulaires au diagnostic chez l'homme, et enfin les différentes atteintes cognitives et comportementales dues à ces anomalies.

Les inscriptions seront cloturées le 15 Mai 2019, ou dès que le nombre maximal d’invités sera atteint (180 personnes).

Les inscriptions doivent se faire sur Eventbrite, comprenant un paiement de 100€ /personne pour les professionnels, ou 35€ / personne pour les étudiants.





Thursday, June 13

Please note: this is only a pre-program, speakers and presentations are subjected to modification.

Welcome & Introduction to IRC5  Lynn Paul, PhD, IRC5 President


Session 1: Brain Development (Chair: Elliott Sherr)

Linda Richards :  “Mutations in human DCC affect cell morphology which may underlie altered interhemispheric remodelling of the septum and agenesis of the corpus callosum”

Alessandra Pierani : "Life and death of transient neurons in the maturation of functional and dysfunctional cortical circuits"

Alain Chedotal : “Role of netrin1 and DCC in axonal wiring: from spinal cord to cortex”

Anais Bellon : "Epigenetic control of cortical wiring: role of axonal miRNAs in fetal alcohol spectrum disorders"


Session 2: Models (Chair: Linda Richards)

Binnaz Yalcin : “Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis

Marta Nieto Lopez : “Developmental plasticity underlies the diversity of cortical maps”

Christine Laclef  : “Role of primary cilia in corpus callosum development”

Sonia Garel : “Microglia at the crossroads of cortical wiring and environmental signals" or "Microglia and prenatal inflammation in cortical wiring"


Session 3: Connectivity and plasticity (Chair: Fernanda Tovar-Moll)

Diego Szczupak : “Assessing interhemispheric connectivity in animal models of dysgenesis of the corpus callosum”

Roberto Lent : "Cortical connectivity changes after severe peripheral traumas "

Gregor Kasprian : " Clinical fetal magnetic resonance imaging of brain connectivity "

Ghislaine Dehaene : “Corpus callosum and functional hemispheric asymmetries in human infants”


Session 4: Long-term outcomes (Chair: Paul Lockhart)

Stéphanie Valence : “Prenatal diagnosis of ACC:  what have they become? Prospective follow-up of a cohort of children born between 2005 and 2015”

Romina Romaniello : “Long-term follow-up of a cohort of subjects affected by corpus callosum agenesis detected during fetal life. Neuropsychological, neuroimaging and genetic correlations”


Friday, June 14


Session 5: Prenatal diagnosis (Chair: Christel Depienne)

Laurent Guibaud : " Prenatal imaging diagnosis of corpus callosum anomalies "

Zvi Leibowitz : “ The many faces of the fetal corpus callosum, on our experience and difficulties in diagnosing and counselling parents of fetuses with suspected callosal anomalies”

Tally Lerman-Sagie : " Autopsy findings in fetuses with agenesis of the corpus callosum diagnosed in utero. "

Laurent Salomon :  " Lumière prenatal imaging platform : Prenatal imaging diagnosis of corpus callosum anomalies"


Session 6: Behavior (Chair : Warren Brown)

Laurence Vaivre-Douret: Patients with ARID1B mutations (Coffin-Siris syndrome): specific neuropsychological and neuropsychomotor deficits correlated with corpus callosum metrics

Lynn Paul

+more to be announced


Clinical Applications (with Families):

Catherine Garel: Imagerie prénatale de l’agénésie du corps calleux : interêt et limitesobstetricien: impact du diagnostic prénatal ?

Tania Attie-Bitach & Solveig Heide : Les outils génétiques : interêt et limites

Delphine Héron:  Diagnostics génétiques devant une agénésie du corps calleux

Lynn Paul & Emmanuelle Lacaze: Aspects cognitifs et comportementaux

Jean-Marie Jouannic : Les grandes étapes du diagnostic prénatal des anomalies du corps calleux

Laetitia Domenighetti : Organisation des maladies rares en France et Europe et Intérêt d’une association

Accompagnement médicosocial

Chloé Girault : Accompagnement médicosocial

Round table with families

Concluding Remarks  Linda Richards, PhD,  IRC5 Secretary




  • Tania Attié-Bitach

    Tania Attié-Bitach

    Université Paris V MD, PhD
  • Anais Bellon

    Anais Bellon

    Université Aix-Marseille PhD
  • Yalcin Binnaz

    Yalcin Binnaz

    Institut de Génétique et de Biologie Moléculaire et Cellulaire Dr
  • Warren S. Brown

    Warren S. Brown

    Fuller Graduate School of Psychology PhD
  • Alain Chedotal

    Alain Chedotal

    Institut de la Vision PhD
  • Ghislaine Dehaene

    Ghislaine Dehaene

    INSERM/Neurospin MD, PhD
  • Christel Depienne

    Christel Depienne

    University Hospital Essen PhD
  • Catherine Garel

    Catherine Garel

    Hopital Armand-Trousseau MD
  • Sonia Garel

    Sonia Garel

    Institut de Biologie de l'Ecole Normale Superieure PhD
  • LG Laurent Guibaud

    Laurent Guibaud

    CHU de Lyon Pr
  • Delphine Heron

    Delphine Heron

    La Pitié-Salpétrière Dr
  • JJ Jean-Marie Jouannic

    Jean-Marie Jouannic

    Hôpital Armand Trousseau Professor
  • Gregor Kasprian

    Gregor Kasprian

    Medical University of Vienna MD
  • EL Emmanuelle Lacaze

    Emmanuelle Lacaze

    Hopital Trousseau
  • CL Christine Laclef

    Christine Laclef

    Institut du Fer à Moulin on the mechanisms of brain development Associate Professor
  • Roberto Lent

    Roberto Lent

    Federal University of Rio de Janeiro MD, PhD
  • Tally Lerman-Sagie

    Tally Lerman-Sagie

    Wolfson Medical Center, Israel Professor
  • Paul Lockhart

    Paul Lockhart

    Murdoch Children's Research Institute PhD
  • Paul Lynn

    Paul Lynn

    California Institute of Technology PhD
  • Marta Nieto-Lopez

    Marta Nieto-Lopez

    Centro Nacional de Biotecnología, PhD
  • Alessandra Pierani

    Alessandra Pierani

    Imagine Institute and Institute of Psychiatry and Neuroscience of Paris PhD
  • Linda Richards

    Linda Richards

    Queensland Brain Institute Professor
  • Romina Romaniello

    Romina Romaniello

    Eugenio Medea Scientific Institute, Bosisio Parini Doctor
  • LS Laurent Salomon

    Laurent Salomon

    Hôpital Necker Pr
  • Elliott Sherr

    Elliott Sherr

    University of California, San Francisco Professor
  • Diego Szczupak

    Diego Szczupak

  • VT Victor Tarabykin

    Victor Tarabykin

    Charité - Universitätsmedizin Berlin MD, PhD
  • LV Laurence Vaivre-Douret

    Laurence Vaivre-Douret

  • SV Stepanie Valence

    Stepanie Valence

    Hopital Trousseau Doctor

Have questions about Cortical Connections Conference 2019? Contact Intn'l Research Consortium for the Corpus Callosum & Cerebral Connectivity

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When & Where

Imagine Institute
24, Boulevard de Montparnasse
75015 Paris

Thursday, June 13, 2019 at 8:45 AM - Friday, June 14, 2019 at 5:30 PM (CEST)

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Intn'l Research Consortium for the Corpus Callosum & Cerebral Connectivity

The International Research Consortium for the Corpus Callosum and Cerebral Connectivity (IRC5) is an international, multidisciplinary effort to discover the causes, consequences, and effective interventions for disorders of the corpus callosum and associated disorders of cerebral connectivity. It was established on March 20, 2015 by a group of investigators who are leading experts in corpus callosum developmental disorders and their neuropsychological and developmental outcomes and who have maintained long-standing involvement in patient support organizations.


IRC5 Mission:

- Identify what causes malformation of brain connections before birth

- Discover ways to prevent or ameliorate these malformations

- Improve accuracy of predicting how child will be impacted by these malformations

- Develop effective interventions to prevent (or minimize) long-term disability from them, such as deficits in cognition and behavior, as well as neurologic conditions such as epilepsy, ataxia and spasticity.


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