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Animal-derived heart valves for the treatment of cardiac patients

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University Archivio Antico - Palazzo Bo

Via 8 febbraio 1848

Padova

Italy

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During the last 4 years, 14 research institutions, including hospitals, universities, research centres and companies from 8 EU and non-EU countries have been elucidating the causes for the premature deterioration of animal-derived bioprosthetic heart valves that precludes their application in young patients.

Programme

14.30 Welcoming remarks
Rosario RIZZUTO, Principal (University of Padua,I)
Luciano FLOR, General Director (Padua University Hospital - Azienda Ospedaliera di Padova, I)

14.40 Introduction to the conference
Emanuele Cozzi, Project Coordinator (Padua University Hospital - Azienda Ospedaliera di Padova, I)

Session I – The use of biological heart valves (BHV) in cardiac patients

Chairmen: Manuel Galiñanes (ICS/HEBRON, ES)
Tomaso Bottio (University of Padua,I)

14.45 Biological versus mechanical heart valves
tbd

15.00 The structural valve deterioration (SVD)
tbd

15.15 Patients receiving BHV: presentation of the TransLink study
Jean Christian Roussel (CHU, F)

Session II - The immune response to BHV

Chairmen: Marta Vadori (AOP, I)
Cristina Costa (IDIBELL, ES)

15.30 Potential glycan targets for antibodies causing SVD (structural valve detoriation (SVD)
Michael Breimer (UGOT, Sw)

15.45 Anti-Neu5Gc antibodies
Vered Karavani (TAU, IL)

16.00 Anti-αGal antibodies and other aspects of the anti BHV immune response
Rafael Mañez (ICS/HUB, E)

16.15 Discussion

16.30-16.45 COFFEE BREAK

Session III – Possible solutions to the structural valve deterioration

Chairmen: Rizwan Hanji (UM, CA)
Yasu Takeuchi (UCL, UK)

16.45 New sources of engineered animal valves
Cesare Galli (AVT, I)

17.00 New drug candidates to protect from BHV
Marta Pascual (IUCT, E)

17.15 What about chemical treatments to prevent BHV?
Gino Gerosa (UniPD, I)

17.30 Discussion

Session IV - Conducting research initiatives in the EU landscape

Chairmen: Emanuele Cozzi (OAP, I)
Melchor Sanchez-Martinez (MtB, ES)

17.45 Coordination of research efforts at a European level: role of the European Commission
To be confirmed European Commission - Research Directorate General

Session V- Closing considerations and future perspectives

Chairmen: Emanuele Cozzi (Padua University Hospital - Azienda Ospedaliera Padova, I)
Jean-Paul Soulillou (INSERM, F)

18.00 Final remarks and conclusion of the Conference
Jean-Paul Soulillou (INSERM, F)

Potential glycan targets for antibodies causing SVD (structural valve detoriation (SVD)

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University Archivio Antico - Palazzo Bo

Via 8 febbraio 1848

Padova

Italy

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