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Advancing Science in Peritoneal Malignancies

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Champalimaud Foundation

Av. Brasília

1400-038 Lisbon

Portugal

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Advancing Science in Peritoneal Malignancies

22nd and 23rd May 2020


Organising Committee

Andreas Brandl - Digestive Unit, Champalimaud Foundation, Lisbon, PT

Carlos Carvalho - Digestive Unit, Champalimaud Foundation, Lisbon, PT

João Casanova - Gynaecology Unit, Champalimaud Foundation, Lisbon, PT

José Filipe Cunha - Digestive Unit, Champalimaud Foundation, Lisbon, PT

Nuno Figueiredo - Digestive Unit, Champalimaud Foundation, Lisbon, PT

Pedro Vieira - Digestive Unit, Champalimaud Foundation, Lisbon, PT


Speakers & Chairs:

Joaquim Abreu de Sousa - Surgical Oncology Service, IPO Porto, PT

Alvaro Arjona-Sánchez - Hospital Universitario Reina Sofía, Córdoba, ES

Marta Carriço - Champalimaud Foundation, Lisbon, PT

Thomas Cecil - Basingstoke and North Hampshire Hospital, Basingstoke, GB

Wim Ceelen - Universiteit Gent, BL

Delia Cortés-Guiral - Fundación Jiménez Díaz Hospital, Madrid, ES

Rita Fior - Champalimaud Foundation, Lisbon, PT

Santiago González-Moreno - MD Anderson Cancer Center, Madrid, ES

Ignace de Hingh - Catharina Kanker Instituut, Eindhoven, NL

Olivier Glehen - Centre Hospitalier Lyon-Sud, Lyon, FR

Brendan Moran - Basingstoke and North Hampshire Hospital, Basingstoke, GB

Marc Reymond - Universität Tübingen, DE

Beate Rau - Charité – Universitätsmedizin Berlin, DE

Paul Sugarbaker - Washington Cancer Institute, Washington, USA

Nancy Vanderpuye - Basingstoke and North Hampshire Hospital, Basingstoke, GB

Kurt Van der Speeten - Ziekenhuis Oost-Limburg, Genk, BE

John Spiliotis - Athens Medical Centre & European Interbalkan Medical Centre, Athens, GR

Yutaka Yonemura - Kishiwada Tokushukai Hospital, Japan, JP

Susanne Marz - Charité, Berlin, DE (TBC)

Kjersti Flatmark - Oslo University Hospital, Oslo, NO (TBC)




Day 1 - 22nd May 2020


09:00 Welcome

Leonor Beleza, President of the Champalimaud Foundation, Lisbon, PT


09:10 Introduction

Brendan Moran, Basingstoke, GB


Session 1 - Treatment Principles of Peritoneal Malignancies

Chairs: Andreas Brandl, PT & Brendan Moran, GB

09:30 Techniques of cytoreductive surgery with peritonectomy procedures

(Paul Sugarbaker, Washington, USA)

10:00 Pharmacology of different techniques of intraperitoneal drug administration

(Kurt Van der Speeten, Genk, BE)

10:20 Standardisation of classification and scores (PCI, CC, Scores, etc.)

(Pedro Vieira, Lisbon, PT)

10:30 Complication Management

(Thomas Cecil, Basingstoke, GB)


Session 2 - Hot Topic: Colorectal Cancer

Chairs: Paul Sugarbaker, USA & Thomas Cecil, GB

10:45 Tumour biology and other selection criteria for CRS & HIPEC

(Santiago González-Moreno, Madrid, ES)

11:05 CRS with or without HIPEC?

(Olivier Glehen, Lyon, FR)

11:25 Multimodal treatment paths – the right place for chemotherapy

(Ignace de Hingh, Eindhoven, NL)


Session 3 - Hot Topic: Gastric Cancer

Chairs: Yutaka Yonemura, JP & Olivier Glehen, FR

11:45 The role of CRS & HIPEC in gastric cancer

(Beate Rau, Berlin, DE)

12:05 HIPEC to prevent peritoneal metastases – is it effective?

(Olivier Glehen, Lyon, FR)

12:25 Efficacy of intraperitoneal chemotherapy application

(Yutaka Yonemura, Japan, JP)

12:45 Is there cure for patients with peritoneal metastasis?

(Andreas Brandl, Lisbon, PT)


13:00–14:00 Lunch Break


Session 4 - Case Presentation

Panel: Beate Rau, DE & Kurt Van der Speeten, BE & Thomas Cecil, GB & José Filipe Cunha, PT & John Spiliotis,GR

14:00 6 cases to be selected (20 minutes each)


16:00–16:30 Coffee Break


Session 5 - Hot Topic: Ovarian Cancer

Chairs: John Spiliotis, GR & Joaquim Abreu de Sousa, PT

16:30 CRS & HIPEC as first line treatment for Ovarian Cancer

(John Spiliotis, Athens, Greece)

16:45 Indications for HIPEC in the treatment of recurrent disease

(João Casanova, Lisbon, PT)


Session 6 - New Trends in the Treatment of Peritoneal Malignancies

Chairs: Kurt Van der Speeten, BE & Delia Cortés-Guiral, ES

17:20 Pressurised Aerosol Chemotherapy (PIPAC) – neoadjuvant, adjuvant or palliative?

(Marc Reymond, Tübingen, DE)

17:40 Minimal Invasive peritonectomy procedures – the future or non-sense?

(Alvaro Arjona-Sánchez, Córdoba, ES)





Day 2 - 23rd May 2020


Session 7 - Perioperative Management of Patients with Peritoneal Malignancies

Chairs: Santiago González-Moreno, ES & Nuno Figueiredo, PT

09:00 Prehabilitation – the key to reduce postoperative complications?

(Delia Cortés-Guiral, Madrid, ES)

09:15 Postoperative challenges – an anesthesiologist´s point of view

(Susanne Marz, Berlin, DE) (TBC)

09:30 Psychoncologic risk evaluation and early detection of postoperative psychologic disorders

(Nancy Vanderpuye, Basingstoke, GB)

09:45 Postoperative nutrition challenges

(Marta Carriço, Lisbon, PT)


10:00–10:30 Coffee Break


Session 8 - Basic Science & Translational Research in PM

Chairs: Alvaro Arjona-Sanchez, ES & Ignace de Hingh, NL

10:30 PDX mouse models – current projects

(Wim Ceelen, Gent, BL)

10:45 Chemosensitivity – the right direction to optimise patient´s treatment

(Kurt Van der Speeten, Genk, BE)

11:05 Zebrafish avatar – a fast and potentially useful tool for peritoneal malignancies

(Rita Fior, Lisbon, PT)

11:20 Insights on the pharmacologic treatment of Pseudomyxoma peritonei from a PDX-model

(Kjersti Flatmark, Oslo, NO) (TBC)


Session 9 - Case Presentation

Panel: Yutaka Yonemura, JP & Olivier Glehen, FR & Brendan Moran, GB & Paul Sugarbaker, USA & Marc Reymond, DE

11:35 5 cases to be selected (20 minutes each)


13:00–14:00 Lunch Break


Session 10 - National and International Registries – the Present and Future Collaborations

Chairs: Carlos Carvalho, PT & Marc Reymond, DE

14:30 The German Experience (National Quality Registration StuDoQ)

(Beate Rau, Berlin, DE)

14:45 The French Experience (Big RENAPE)

(Olivier Glehen, Lyon, FR)

15:00 The British Experience (National MDT and CRC Registry)

(Thomas Cecil, Basingstoke, GB)

15:15 The Dutch Experience (National Cancer Registry)

(Ignace de Hingh, Eindhoven, NL)


15:30 Closing Remarks

Andreas Brandl, Lisbon, PT




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Champalimaud Foundation

Av. Brasília

1400-038 Lisbon

Portugal

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