Advances in Drug Development and Delivery: Innovation and Patient-Focus

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JLABS @ Toronto

661 University Avenue

Suite 1300

Toronto, M5G 0B7

Canada

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Advances in Drug Development and Delivery:
Challenges, Patient-Centricity, and Innovative Technologies
JLABS- Toronto
Toronto, Ontario
November 30, 2017

Program Overview:
Making the right choices is important in today’s R&D environment, especially considering the various pressures on developers such as time, resources, and funding. Short term thinking can lead to long term problems leading to missed timelines, escalating costs, and even regulatory issues in later phases. These factors can unfortunately contribute to non-optimal drug products unless they are addressed upfront by incorporating patient focused design principles to promote better drug performance and patient outcomes.

This event will focus on a number of key considerations for developing the best small or large molecule drug product for patients:
• Avoiding the biggest pitfalls in drug development
• Addressing biopharmaceutical challenges
• Incorporating patient considerations in designing a drug product
• Latest trends and technologies for small and large molecule therapeutics

Exclusively for JLABS residents – Meet with a Catalent expert: Attendees have the opportunity to discuss their projects and challenges and learn about potential solutions in a 1-on-1 setting with a Catalent formulation or biologics expert. This is a complimentary opportunity for all attendees. Advanced scheduling is requested. Please email Ronak Savla (ronak.savla@catalent.com) or Dan Peizer (dan.peizer@catalent.com).


Program Agenda
8:00 am – 8:30 am | REGISTRATION & BREAKFAST
8:30 am – 8:45 am | WELCOME & INTRODUCTION
Prof. Christine Allen, Professor and GSK Chair in Pharmaceutics and Drug Delivery, University of Toronto
Breanne Halyk, Innovation Activation Manager, JLABS Canada

SMALL MOLECULE DRUG DEVELOPMENT CONSIDERATIONS
8:45 am – 9:15 am | DELIVERING THE “PROMISE OF R&D”
Dr. Cornell Stamoran, Founder, Catalent Institute

9:15 am – 10:00 am | FORMULATION TECHNOLOGIES TO OVERCOME ORAL BIOAVAILABILITY CHALLENGES OF SMALL MOLECULE DRUGS
Mr. Stephen Tindal, Director, Science & Technology, Catalent Pharma Solutions

10:00 am – 10:15 am | BREAK

10:15 am – 11:00 am | DESIGN OF AMORPHOUS SOLID DISPERSIONS FOR ENHANCING THE DELIVERY OF POORLY SOLUBLE DRUGS: EFFECT OF SOLUBLE VERSUS INSOLUBLE CARRIERS
Prof. Ping Lee, Professor in Pharmaceutics and Drug Delivery, University of Toronto

11:00 am – 12:00 pm | PATIENT FOCUSED DOSE FORM DESIGN
Dr. Cornell Stamoran, Founder, Catalent Institute

12:00 pm – 1:30 pm | NETWORKING LUNCH & MEET THE EXPERTS

LARGE MOLECULE DRUG DEVELOPMENT CONSIDERATIONS
Chair by Prof. Isabelle Aubert, Professor Laboratory Medicine and Pathobiology, University of Toronto

12:00 pm – 1:30 pm | REGISTRATION, NETWORKING LUNCH & MEET THE EXPERTS

1:30 pm – 2:15 pm | EFFICIENT EXPRESSION OF COMPLEX PROTEINS IN MAMMALIAN CELLS
Dr. Greg Bleck, Global Head R&D, Biologics, Catalent Biologics

2:15 pm – 3:00 pm | ANTIBODY-DRUG CONJUGATES
Dr. David Rabuka, Global Head R&D, Chemical Biology, Catalent Biologics

3:00 pm – 3:15 pm | BREAK

3:15 pm – 4:00 pm | THERAPEUTIC DISCOVERY USING SYNTHETIC ANTIBODY REPERTOIRES
Dr. Jarrett Adams, Associate Director, Toronto Recombinant Antibody Centre

4:00 pm – 5:00 pm | PANEL DISCUSSION
Moderated by Prof. Isabelle Aubert

5:00 pm | CLOSING REMARKS

Meet with a Catalent expert: Attendees have the opportunity to discuss their projects and challenges and learn about potential solutions in a 1-on-1 setting with a Catalent formulation or biologics expert. This is a complimentary opportunity for all attendees. Advanced scheduling is requested. Details to follow.



Date and Time

Location

JLABS @ Toronto

661 University Avenue

Suite 1300

Toronto, M5G 0B7

Canada

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