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19th International Conference on Medicinal Chemistry & Multi Targeted Drug...

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San Francisco

San Francisco, CA

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19th International Conference on Medicinal Chemistry & Multi Targeted Drug Delivery


About Conference

Conference Series LLC Ltd welcome professional chemists, researchers, professors, scientific communities, delegates, students, business professionals and executives from all over the world to attend the 19th International Conference on Medicinal Chemistry and Multi-Targeted Drug Delivery scheduled during November 05-06, 2018 in San Francisco, USA

Medicinal chemistry explores different ways how chemists are modifying molecules structure so as to design innocuous and effective drugs. It is one of the most rapidly developing areas within chemistry, both globally and locally.The different spectroscopic techniques for drug design, synthesis and characterization of novel therapeutic agents including small molecules, peptide drugs and natural products will be discussed. Applications in novel methods of drug delivery systems and formulations for better bioavailability of bioactive compounds are also welcomed

Medchem And MTDD will likewise give the fantastic chance to meet specialists, trade data, and reinforce the coordinated effort among Directors, Researchers, Associate Professors, and Scholars from both scholarly community and industry.

Medchem And MTDD will cover all areas of Medicinal chemistry

Conference Highlights are:

· Medicinal Chemistry and Drug Discovery

· Principles of Medicinal Chemistry

· Medicinal Chemistry Aspects of Drug Action and Drug Metabolism

· Drug Metabolism

· Molecular Biology - A New Route to Drug Discovery

· Fusion of Traditional And Biomedicine

· Plant Genomics

· Pharmaceuticals Vs Nutraceuticals

· Frontiers In Chemistry

· Computer Aided Drug Designing

· Drug Chemistry

· Hyphenated Chromatographic Techniques

· Cancer Studies: Drug Delivery Chemistry

· Neuro Degenerative Disease

· Vaccines And Autism

· Emerging Infectious Diseases

Target Audience:

· Eminent Scientific Professionals in Pharma and Chemistry

· Faculty (Professors, Associate Professors, Asst. Professors )

· Pharma and Chemistry Colleges & Training Institutes

· Pharmaceutical and Chemistry Associations and Societies

· Pharmaceutical Business Entrepreneurs

· Manufacturing Pharmaceutical products Companies

· Manufacturing Medical Devices Companies

· Pharma and Chemistry Students

· PhD Scholars, Graduates and Post Graduates

· Directors, CEO’s of Organizations

· Association, Association presidents and professionals

· Noble laureates in Health Care and Medicine

· Bio instruments Professionals

· Bio-informatics Professionals

· CRO and DATA management Companies

· Data Management Companies

Conference Series LLC Ltd organises 800+ Conferences every year across USA, Europe & Asia with support from 1000 more scientific societies and publishes 400+ Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Sessions / Tracks

Track 1 Medicinal Chemistry and Drug Discovery

  • Target discovery and validation
  • Molecular modelling
  • Drug receptor interactions
  • Pro drug synthesis and drug targeting
  • Structure and Fragment based drug design

Track 2: Structure-based drug design, virtual screening

  • Organic synthesis of ligands and inhibitors
  • Protein biochemistry.
  • Development of screening and assay methods.
  • Molecular biology and genetic engineering.
  • Drug-Receptor Interactions
  • Signal Transduction and Second Messengers
  • The Biological Evaluation of New Compounds
  • Considerations for the Use of Computational Chemistry Techniques by Medicinal Chemists

Track 3: Medicinal Chemistry Aspects of Drug Action and Drug Metabolism

  • Research strategies
  • Methodologies and literature concerning the mechanisms of drug action and drug metabolism
  • Mechanisms of drug action and drug metabolism in opiate drugs and beta blockers

Track 4: Drug Metabolism

  • NS3, the protease of flaviviruses such as dengue and West Nile virus
  • Combined phenotypic/target-oriented screening approaches, and their application on anti-infective drug discovery
  • Targeting of host factors involved in virus replication
  • Biochemical mechanisms for the biotransformation of drugs and foreign compounds
  • reaction mechanisms
  • Ultrastructural considerations,induction mechanisms, methodology, kinetics of inhibition
  • Activation, steroid and amine metabolism.

Track 5: Molecular Biology - A New Route to Drug Discovery

  • DNA Structure
  • What Determines the Differences between Cell Types
  • Gene Cloning - Propagation of Genetic Material in Alternative Host Systems
  • Expression of Cloned Genes
  • Uses of Cloned Human Proteins

Track 6 Fusion of Traditional And Biomedicine

  • Personalized Medicine
  • Naturopathy and Acupuncture as a secondary medical system
  • Drug resistance by misuse of medications
  • Modernising Traditions
  • Protection and piracy

Track 7 Plant Genomics

  • Plant-pathogen interactions
  • Breeding strategies to enhance yield
  • Hybrid vigor
  • DNA microarrays
  • Advances in plant Tissue culture and revolutionizing agriculture
  • Plant biotech for agriculture Improvement

Track 8 Pharmaceuticals Vs Nutraceuticals

  • Can only drug cure a disease?
  • Antioxidants
  • Why are pharmaceuticals around?
  • Nutraceutical Supplements as convenient and effective
  • Bridging the gap between food and medicine

Track 9 Frontiers In Chemistry

  • Peptides with dual Antimicrobial and anticancer activities
  • Anticancer activitiy of maize Bioactive peptides
  • Contemporary materials safety
  • The 'making a murderer 'case:A brief description on how EDTA is measured in blood

Track 10 Computer Aided Drug Designing

  • Ligand and structure based drug design
  • Computational Chemistry
  • Molecular modelling
  • Enzyme as target
  • Receptor as target
  • QSAR/QSPR Quantitative structure activity/property relationships

Track 11 Targeted Drug Delivery System-TDDS (Smart Drug Delivery)

  • Platinum based anticancer drugs
  • Objectives of TDDS
  • Bioligand and its attachement to protein target
  • Passive ,Inverse and Active approaches of targeting
  • Chemical and physical enhancer pathways

Track 12 Drug Chemistry

  • ADME (adsorption,distribution,metabolism and excretion)Of drugs
  • Metabolism and toxicology
  • Antiviral and antimicrobial activity
  • Drug receptor interaction
  • Kojic acid as a tyrosine inhibitor

Track 13 Hyphenated Chromatographic Techniques

  • GC-MS
  • LC-ITIR
  • LC-MS
  • LC-NMR
  • Chemical fingerprinting and quality control

Track 14 Cancer Studies: Drug Delivery Chemistry

  • Magnetoelectric nanoparticles
  • Nanoparticle drug delivery
  • Problems of multidrug resistance in cancer therapies
  • Taxoids as potent cytotoxic agents for tumour targeting drug delivery

Track 15 Neuro Degenerative Disease

  • Dementias responsible for greatest burden of neurodegenerative diseases
  • Causes and treatments
  • Motor neurone diseases
  • Huntington’s disease.

Track 16 Vaccines And Autism

  • A pattern of depressed resistancein autism
  • Do vaccines for children cause autism?
  • Research supports vaccinating
  • Autism genetic risk factors
  • Autism environmental risk factors

Track 17 Emerging Infectious Diseases

  • Determinants of Infectious diseases
  • Emergence and Reemergence of infectious diseases
  • HIV/AIDS:Newly emerging infectious diseases
  • Research on emerging Infectious diseases
  • Preventing emerging infectious diseases:A strategy for the 21st century
  • Zika virus

Track 18 Antibiotics

  • How do antibiotics work?
  • What are the side effects?
  • Main types of antibiotics
  • Biological antibiotics derived from molds
  • Synthetic antibiotics derived from dyes
  • Antibiotic resistance and meggence of 'superbugs'

Track 19 Personalised Medicines And Drugs

  • Personalised medicines:A decade of advancements
  • Cancer genomics
  • Pharmacogenomics
  • Good for patients but bad for drug companies
  • Ramifications of illicit drug markets in society

Track 20 Medchem-Antimicrobial And Infectious Agents

  • Chemotherapeutic agents
  • Microorganisms that produce antibiotics
  • Antimicrobialpeptides:Promising compounds against pathogenic microorganisms
  • Discovery of penicillin
  • Discovery of sulphonamides

Track 21 Chem Virology (zika virus)

  • Rapid Transmission
  • ZIKV-Processing on the microfluidic cassette
  • ZIKA virus infection may prevent reinfection
  • Zika infection-A global threat to human population
  • Major possible symptoms
  • Drugs and vaccines available so far

Track 22 New Trends In Pharmacology And Drug Development

  • Binding kinetics and pathways of ligands to GPCRs
  • Aurora A kinase ,a priority pharmaceutical target for treatment of cancer
  • Novel adjuvants designed for improving vaccine efficacy
  • Targetting Protease-activated receptors(PAR1)
  • Risks associated with new drug development

Track 23 Novel Drug Discovery And Drug Delivery

  • Role of computational biology
  • Drug delivery carriers
  • Pioneering digital health and smart drug delivery systems
  • Ligand binding studies
  • Phage display technology for clinical application of protein drugs

Track 24 Chemical Biology

  • Potential use of stem cells for regeneration
  • Harnessing yeast organelles for metabolic engineering
  • Si-RNA a tool in chemical biology
  • Discovery of biomolecules through metagenomics
  • Protomics

Track 25 Novel Research: Hit To Lead

  • High throughput screening
  • Target identification
  • Target validation
  • Assay development
  • Screening cascade-Lead optimization

Track 26: Advanced Medicinal Chemistry

  • Application of integrated data from the physical and biological sciences to problems of chemotherapy
  • Transport of drugs to site of action
  • Biotransformation of drugs
  • Interaction of drugs with enzyme systems
  • Recent advances in drug design

Track 27: Scientific Drug Discovery Breakthroughs For Deadly Diseases

  • New Drugs to Eliminate Malaria
  • Breakthrough in the Treatment of Cancer
  • New Strategy for the Discovery of Drugs
  • New Drug Discovery Technique to Target a Class of Enzymes
  • Serelaxin - Breakthrough Therapy in the Treatment of Heart Failure
  • Vertex Pharmaceuticals’ New Drug Combination can Treat Cystic Fibrosis
  • Promising Treatment for Multiple Sclerosis
  • Discovery of Ebola Protein could Lead to Drug Development
  • New Drug could Treat Most Aggressive Form of Lung Cancer
  • Medicinal chemistry of drugs used in diabetic cardiomyopathy.

Track 28: Fluorine in Medicinal Chemistry: Recent Therapeutic Applications of Fluorinated Small Molecules

  • Advantages of fluorine in drug development
  • Fluorinated drugs in the central nervous system (CNS)
  • Fluorinated drugs in the treatment of metabolic and cardiovascular diseases
  • Fluorinated drugs in the treatment of cardiovascular diseases
  • Fluorinated antibacterial agents
  • Fluorinated azole antifungal agents
  • Fluorinated anti-inflammatory agents
  • Fluorinated anticancer agents

Track 29: Human Cytochrome P-450 Biochemistry

  • Current problems in human drug metabolism by cytochrome P-450 enzymes
  • Hypothesis testing and experimental problem solving in the areas of enzyme kinetics and mechanism

Track 30: Immunizing and Antimicrobial Agents

  • Mechanisms of action
  • spectrum of coverage, resistance patterns
  • Toxicity, and therapeutic applications of antibiotics, antifungals, and antivirals
  • chemical and biologic properties of agents used to prevent or treat infectious diseases

Track 31: Biophysical Enzymology and Biopharmaceuticals

  • Therapeutic antibodies, and drug targets
  • Protein-protein-interactions and Protein-lipid interaction.
  • Thermodynamics and kinetics of protein-ligand interactions,

Track 32: Integrated Pharmacology

  • Integrates aspects of medicinal chemistry and pharmacokinetics with the physiology, Pharmacology, and genetics of therapeutic drug targets.
  • Include ion channels and enzymes relevant to cardiovascular disease
  • Include ion channels and enzymes relevant neurodegenerative disease

Track 33: Diagnostic Medicinal Chemistry

  • Biological Mass Spectrometry
  • Modern ionization methods and mass analyzers
  • Small molecule structure assignment
  • Quantitative assay development by LC-MS and metabolomics quantitative discovery-based proteomics and validation methods
  • Peptide sequence determination
  • Post-translational modification mapping
  • Protein structure determination methods

Track 34: Anticancer and Anti-Diabetic Agents

  • Design and synthesis of target compounds: thiazoles, thiophenes, benzimidazoles and boronic acid derivatives as anticancer and anti-diabetic agents.
  • Synthesis of neuroprotective and multi target directed ligand molecules and their pharmacokinetic/pharmacodynamic (PK/PD) studies.
  • Ionic liquid mediated C-C and C=C bond forming reactions.
  • Re purposing of existing drug molecules for improved PK/PD profiling by modification of non pharmacophoric parts.
  • Transition metal catalyzed C-H activation reactions of unreactive (C(sp2)-H, C(sp3)-H bond) for the synthesis of anticancer agents.

Track 35: Immunotherapy-Oncology

  • Monoclonal antibodies
  • Non-specific immunotherapies
  • Oncolytic virus therapy
  • T-cell therapy
  • Cancer vaccines

Track 36: Sources of leads

  • Lead selection from HTS and virtual screening
  • General design principles
  • Drug design with defined target structure
  • Drug design without defined target structure
  • ADMET Optimization

Track 37: Drug Biotransformation and Disposition

  • High resolution-mass spectrometry (HR-MS) technology
  • Data-mining tools
  • Data-acquisition techniques.
  • LC/MS
  • AB SCIEX TripleTOF™ 5600 System for the study of drug metabolism in BDC rats and CYP inhibition cocktail assays.

Track 38: Epigenetic gene silencing in cancer

  • Histone deacetylases (HDACs) and histone acetylases (HATs)
  • Leukaemia-associated fusion proteins
  • Leukaemia-associated fusion proteins HDAC inhibitors
  • Tumour-necrosis factor-related Apoptosis-Inducing Ligand (TRAIL) and FAS death receptor pathways

Track 39: Nanotechnology in Drug Delivery Systems

  • Nanoparticles that deliver three anti-cancer drugs to the lymph nodes
  • Sustained drug delivery using a hydrogel
  • Photosensitizing agent to enhance the ability of drug carrying nanoparticles
  • Carbon nanofibers penetrate diseased cells
  • Nanotechnology in Drug Delivery - Heart Disease:
  • Nanotechnology in Drug Delivery - Aging and other areas

Track 40: Pharmacology

  • Pharmacokinetics
  • Pharmacodynamics
  • Therapeutics
  • Chemotherapy
  • Toxicology
  • Pharmacogenetics
  • Posology

Track 41: Medical Devices for Drug Delivery

  • Anaesthetic vaporizer
  • Tinctures‎
  • Transdermal patches‎
  • Nasal sprays‎
  • Micro dispensing
  • Syringe

Track 42: Survey of Therapeutics

  • Survey of major drug classes with emphasis on molecular mechanisms of action
  • Target identification with chemical probes
  • Survey of methods used in contemporary pharmaceutical research including computational and combinatorial approaches
  • High-throughput analysis of drug efficacy and metabolism


Please contact the event manager Marilyn (marilyn.b.turner@nyeventslist.com ) below for:
- Multiple participant discounts
- Price quotations or visa invitation letters
- Payment by alternate channels (PayPal, check, Western Union, wire transfers etc)
- Event sponsorships

NO REFUNDS ALLOWED ON REGISTRATIONS
Service fees included in this listing.
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