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10 th Tissue Repair and Regeneration Congress (CSE) A

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10 th Tissue Repair and Regeneration Congress

ABOUT CONFERENCE:

10th Tissue Repair and Regeneration Congress invites all the participants from all over the world to attend during June 10-12, 2019 in Helsinki, Finland , which includes prompt keynote presentations, Oral talks, and Poster presentations.

Tissues are defined as aggregations of similarly specialized cells which collectively function to connect, support or surround other structures and organs of the body. Tissues include tendons, ligaments, fascia, skin, fibrous tissues, fat, , muscles, nerves and blood vessels. Stem cells are cells originate in all multi-cellular organisms. They were isolated in mice in 1981 and in humans in 1998. In humans there are several types of stem cells, each with variable levels of potency. Stem cell treatments are a type of cell therapy that introduces new cells into adult bodies for possible treatment for sicknesses. Stem cells have been used to repair tissue damaged by disease.

WHY TO ATTEND?

10th Tissue Repair and Regeneration Congress has the platform to fulfill the needs in the transformation of this science of hope, to serve promptly with solutions to all the needs. Tissue Repair 2018 will have participants across the world to discuss the Congress goal.

About Organizers

ME Conferences is one of the leading Open Access publishers and organizers of international scientific conferences and events every year across USA, Europe & Asia . Conference Series has so far organized 3000+ Global Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on Medical, Pharma , Engineering, Science, Technology and Business with 700+ peer-reviewed open access journals in basic science, health, and technology.

Scientific Sessions

Tissue Repair 2018 will encompass recent researches and findings in Tissue Repair and Regeneration technologies, stem cell therapies and transplantations and other advancements in stem cell research and Tissue science. Tissue Repair 2018 will be a great platform for research scientists and young researchers to share their current findings in this field of applied science. The major scientific sessions in Tissue Repair 2018 will focus on the latest and exciting innovations in prominent areas of Tissue science and stem cell research.

Target Audience

Eminent personalities
Directors
CEO
President
Vice-president
Organizations
Professors
Research scientists
Tissue science , stem cell line companies Stem Cell laboratory heads
Professors
Students other affiliates related to the area of Stem cell research.


Session/Tracks

TRACK 1-Tissue Repair and Regeneration
Tissue repair denotes to the spare of damaged tissue via dwelling tissue and contains two important components - Regeneration and restore. The differentiation between the two is based totally at the resultant tissue. In Regeneration, specialized tissues is replaced by the proliferation of surrounding undamaged specialized cells. In repair, misplaced tissue is replaced by granulation tissue which matures to form scar tissue. Cells are constantly dying to be able to keep us alive. The stomach creates a new lining each five days(If the stomach linings will not changed into new usually then, hydrochloric acid from the stomach juices would burn a hole inside the stomach, which might soon purpose death). Skin replaces itself every 30 days. The red blood cells have a existence span of one hundred twenty days, and must then be replaced. Each of the distinctive tissues of the frame has its personal natural lifestyles cycle. it's far the goal of regeneration remedy to stimulate the process of self-renewal.

TRACK 2-Stem cell in Tissue Repair
Stem cells are defined as being clonogenic , having self-renewal capacity throughout lifetime and giving rise to terminally differentiated cells of various cell lineages. Their differentiation pathway is unidirectional, passing through the stage of lineage and finally generating differentiated cells. Adult stem cell differentiation is traditionally believed to be restricted to the tissue in which the stem cells reside ( hematopoietic stem cells generate blood cells, liver progenitor cells produce hepatocytes and ). Hematopoietic stem cells are the most thoroughly characterized adult progenitor cells, mostly because of their easy accessibility and use for transplantation to treat malignant disease.

TRACK 3 -Tissue culture and Preservation
Appropriately preserved stem cells can be later used in the field of regenerative medicine for treating congenital disorders, heart defects etc. Cryopreservation of ovarian tissue would have many benefits for infertility treatment. A direct application of such a technique would be in overcoming infertility in cancer patients rendered infertile by harmful treatments such as chemotherapy and radiotherapy which indiscriminately destroy diseased as well as healthy cells. The ability to cryopreserve pre implantation embryos from both animal and human sources has helped to overcome some of the practical concerns.

TRACK4-Cell and Organ regeneration
Evolving evidence suggests that bone marrow–derived endothelial, hematopoietic stem and progenitor cells contribute to tissue vascularization during both embryonic and physiological processes. Recent preclinical and pioneering clinical studies have shown that introduction of bone marrow–derived endothelial and hematopoietic progenitors can restore tissue vascularization after ischemic events in limbs, retina and myocardium . Co conscription of angiocompetent hematopoietic cells delivering specific angiogenic factors enables combination of endothelial progenitor cells (EPCs) into newly sprouting blood vessels. Identification of cellular mediators and tissue-specific chemokines, which facilitate selective recruitment of bone marrow–derived stem and progenitor cells to specific organs, will open up new avenues of research to accelerate organ vascularization and regeneration. As well, identification of factors that promote differentiation of the progenitor cells will permit functional incorporation into neo-vessels of specific tissues while diminishing potential toxicity to other organs. In this review, we deliberate the clinical potential of vascular progenitor and stem cells to restore long-lasting organ vascularization and function.

TRACK5-Application of Tissue engineering
Tissue Engineering is addressed to create functional tissues which include cells, scaffolds, and bioactive molecules .It is the development of biological substitutes that maintains, improves or restores tissue functions resulting in sidestepping the problems associated with tissue damage. In the present, it is treated with transplants, mechanical devices or surgical reconstructions, these three medical therapies have saved and improved countless patients lives with few associated problems. For example, transplantation in organs shows limitations such as transplant rejections and lack of donor to cover all the worldwide demand. Mechanical devices are not capable of accomplishing all the functions related with the tissue and also the prevention of progressive deterioration in patients. Thus it has informed that Tissue Engineering arises from the need to provide more definitive solutions to tissue repairs .

TRACK 6-Biomaterials in Tissue engineering
Biomaterials , an engineered material used to make gadgets to supplant some portion of a living framework or to work in suggest contact with living tissue. The study of biomedical materials includes an investigation of the piece and properties of materials and the manner by which they associate with nature in which they are set. The most widely recognized classes of materials utilized as biomedical materials are polymers, metals, and earthenware production. These three classes are utilized separately and in blend to frame the greater part of the implantation gadgets accessible today.

TRACK 7- Regenerative Medicine
Regenerative pharmaceutical goes for helping the body to shape new tissue to replace lost ones. This will give curative treatment to conditions where current treatments are lacking. Human body has an endogenous arrangement of recovery through foundational microorganisms, where undeveloped cells are discovered nearly in every kind of tissue. The thought is that upgrading of capacity is best proficient by these cells. Regenerative prescription involves the utilization of tissue designing and undifferentiated organism innovation. This audit isn't intended to be thorough, however means to feature present and future utilizations of undifferentiated cells in this energizing new train. Recovering ischaemic coronary illness can be accomplished by conveying society extended MSCs into the coronary supply routes or straightforwardly into the myocardium to grow the endogenousre generative pool.

TRACK 8-Regeneration and Therapeutics
Stem cell–based therapy has been studied to achieve a alternative to current solutions offered by modern medicine .The use of adult stem cells focused on for regeneration . This unique population of multipotential cells has been isolated from various sources, including bone marrow, adipose, and muscle tissues. Genetic engineering of adult stem cells has led to repair and rapid formation in vivo. It is hypothesized that these genetically modified cells exert both an autocrine and a paracrine effects on host stem cells, leading to an effect. The use of direct gene delivery has also shown much promise for in vivo repair. Several viral and non viral methods have been used to achieve substantial bone tissue formation in various sites in animal models. To advance these platforms to the clinical setting, it will be mandatory to overcome specific hurdles, such as control over transgene expression, viral vector toxicity, and prolonged culture periods of therapeutic stem cells. This review covers a prospect of cell and gene therapy for repair .

TRACK 9-Tissue Banking
Tissue banking is the activity of processing, storage and distribution of transplantable human tissues. Tissues retrieved from the human body are used to repair and or replace the diseased or lost tissues of living human body and have saved many precious lives. The common tissues used are cornea, skin, bones, cartilage, joints, heart valves, fascia, tendons, and from human cadaver.

TRACK 10- Stem cell Therapy
Stem cell therapy is the use of stem cells to treat disease . Bone marrow transplantation is the most used stem-cell therapy, but some therapies derived from Umbilical cord blood are also in use. Research is proceeding to develop various sources for stem cells, and to put on stem-cell treatments for Neuro generative disease and conditions such as diabetes, heart disease and other conditions. Stem-cell therapy has become controversial following developments such as the ability of scientists to isolate and culture embryonic stem cell to create stem cells using somatic neuclear transfer and their use of techniques to create Induced pluripotent stem cell.

TRACK 11-Biological Tissue Substitute
The repair or replacement of damaged skins is still an important, challenging problem. Immune acceptance and long-term existence of skin grafts represent the major problem to overawed in grafting given that in most situations auto grafts cannot be used. The rise of artificial skin substitutes provides alternate treatment with the ability to diminish the dependency on the growing demand of cadaver skin grafts. Over the years, considerable research efforts have focused on strategies for skin repair or permanent skin graft transplantations. Accessible skin substitutes include pre- or post-transplantation treatments of donor cells, stem cell-based therapies, and skin counterparts composed of bio-engineered cellular skin substitutes. However, skin substitutes are still prone to immunological rejection, and as such, there is currently no skin substitute available to overcome this phenomenon. This emphases on the mechanisms of skin rejection and tolerance induction and outlines in detail current available tactics and alternatives that may allow achieving full-thickness skin replacement and repair.

TRACK 12-Cellular basis of Tissue Repair
The cellular and molecular basis of trans differentiation will allow to reprogram cells for transplantation. This approach will complement the use of embryonic and adult stem cells in the treatment of degenerative disorders.

TRACK 13-Growth factors for Healing
These are protein molecule comprehensive by the body, it practicalities to control cell division . It can also be designed by genetic engineering in the laboratory and used in biological therapy. Growth factors fix to receptors on the cell surface, with the result of activating cellular proliferation and differentiation. Those growth factors are proteins that will help the cell to growth and proper function as growth stimulators and growth inhibitors, stimulate cell migration, act as chemotactic agents, inhibit cell migration, inhibit invasion of tumor cells, modulate differentiated functions of cells, involved in apoptosis, involved in angiogenesis and promote survival of cells without impelling expansion and differentiation.

TRACK 14- Bone Tissue Engineering
Tissue building has gone to the fore as of late with new methodologies for once more skeletal tissue development trying to address the neglected requirement for bone expansion and skeletal repair. These methodologies try to bridle undifferentiated cells, imaginative platforms and organic components to make, in a perfect world, vigorous, reproducible and upgraded bone development procedures to enhance the personal satisfaction for a maturing populace. Improvements in bone tissue building and recovery, concentrating on skeletal immature microorganisms, vascular advancement and bone development.

TRACK 15-Regeneration Rehabilitation
Regenerative rehabilitation is the values as of rehabilitation and regenerative medicine, with the ultimate goal of developing innovative and operative methods that promote the restoration of function through tissue regeneration and repair. In order to provide an optimal microenvironment for healing tissues, physical therapists use directed therapy to maximize productivity of the body's innate healing processes. Rehabilitation coupled with regenerative medicine surgeries has shown improved outcomes for tissue regeneration. With innovative findings from medical researchers in tissue engineering and cellular therapies, physical therapists play an important role in translating these findings.

AGENDA 2017

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2019 Upcoming Soon
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Day 1 September 11, 2017

08:30-08:45 Registrations
08:45-09:00 Opening Ceremony
Parkinson’s disease: How far can stem cells take us?
Claire Henchcliffe, Weill Cornell Medical Center, USA
09:40-10:20 Title: Combined therapeutic medical device and stem cells for regenerative nanomedicine
Nadia Benkirane-Jessel, Inserm - French National Institute of Health and Medical Research, France
10:20-11:00 Title: Minimal invasive TANONGSAK technique for reduction malarplasty
Tanongsak Panyawirunroj, Asia Cosmetic Hospital, Thailand
Group Photo & Refreshment Break 11:00-11:15 @ Seletar Foyer
Sessions:
Regenerative Medicine | Stem Cell Therapy | Tissue Engineering
Session Introduction
Session Chair: Claire Henchcliffe, Weill Cornell Medical Center, USA
Session Co-chair: Nadia Benkirane-Jessel, Inserm - French National Institute of Health and Medical Research, France
Symposium on
Regenerative Medicine and Its Resources in Promoting Personalized Healthcareand Biopharma (11:15- 13:00)
11:15-11:20 Introductory speech
11:20-11:40
Title: Russia’s landscape in regenerative medicine
11:40-12:00
Title: Laser Structuring Technologies for Tissue Engineering
Peter Timashev, I.M. Sechenov First Moscow State Medical University, Russia
12:00-12:20
Title: Mass spectrometry in regenerative medicine to promote translational resources to be implemented
into personalized heathcare
Ilgar S. Mamedov, LLC Chromsystemslab, Russia
12:20-12:40
Title: Scaffold-free, label-free and nozzle-free biofabrication technology based on magnetic levitational
assembly
Vladimir Mironov, 3D Bioprinting Solutions, Russia
12:40-13:00 Title: Tissue engineered urethral substitution: Recent trends and our results
Denis Butnaru, I.M. Sechenov First Moscow State Medical University, Russia
Lunch Break 13:00-14:00 @ Atrium Restaurant
Title: Antibodies with functionality as unique biomarkers and targets in drug discovery and regenerative
medicine
Sergey Suchkov, I.M. Sechenov First Moscow State Medical University, Russia
14:20-14:40 Title: Regenerative medicine and its armamentarium in promoting personalized pediatric healthcare
Vladimir Sukhorukov, I.M. Sechenov First Moscow State Medical University, Russia
14:40-15:00 Concluding Remarks and Discussion
Special Session
15:00-15:45 Title: Stem cell therapy for the treatment of severe tissue damage after radiation exposure
Alain Chapel, IRSN- Institute of Radioprotection and Nuclear Safety, France
Networking & Refreshment Break -15:45-16:00 @ Seletar Foyer
Young Researcher Forum
Sessions:
Tissue Regeneration | Bone Transplantation | Tumor Cell Science
Session Introduction
YRF Session Chair: Sergey Suchkov, I.M. Sechenov First Moscow State Medical University, Russia
15:45-16:05
Title: Integrative approaches through transcriptome profiling to identify subset-specific gene activity in
myeloma
Siti Sarah Daud, National University of Singapore, Singapore
16:05-16:25 Title: Targeting the unique properties of glucose in cancer through calcium-PP2A-RIPK1 pathway
Lee Ha Yin, Duke–NUS Medical School, Singapore
16:25-16:45
Title: A 3D investigation of islet vasculature in a regenerating rat pancreas after 90% partial
pancreatectomy (PPX)
Viantha Naidoo, University of Cape Town, South Africa
16:45-17:05 Title: Synthesis of TiO2
nanotubes over Ti6Al4V surface to improve osteocompatibility of bone implants
Sahely Saha, National Institute of Technology, Rourkela, India
17:05-17:25 Title: Cellular aging of the immune system: Causes and consequences
Renu Balyan, National University of Singapore, Singapore
17:25-17:45
Title: Derivation of mesenchymal stem cells from umbilical cord by comparing two enzyme digestion
methods: Differentiation of osteogenic cells from UC MSCS
Fathima Zahara Mansoor, Nawaloka Green Cross Labs, Sri Lanka
Panel Discussion

Day 2 September 12, 2017
Seletar
Keynote Forum
09:00-09:40 Title: Transforming tissue repair into truly regeneration with L-PRF
Nelson Pinto, University of the Andes, Chile
09:40-10:20 Title: Regulatory considerations for regenerative therapeutics: US perspective
Debra Webster, Cardinal Health Regulatory Sciences, USA
10:20-11:00 Title: Polyamine mediated regulation of wound healing
Leah Vardy, A*STAR, Singapore
Networking & Refreshment Break 11:00-11:15 @ Seletar Foyer
Sessions:
Cell & Organ Regeneration | Tissue Repair & Regeneration | Advances in Stem Cell | Rejuvenation- Fight Aging
Session Introduction
Session Chair: Alain Chapel, IRSN- Institute of Radioprotection and Nuclear Safety, France
Session Co-chair: Nelson Pinto, University of the Andes, Chile
11:15-11:35
Title: Quiescent pluripotent stem cells capable of expressing SOX2, OCT4, KLF4 and c-Myc reside within
peripheral nerves in adult mammals and can differentiate into cells of all 3 germ layers
Michael H Heggeness, University of Kansas School of Medicine, USA
11:35-11:55 Title: New developments in biologic approaches to articular cartilage regeneration
Susan Chubinskaya, Rush University, Uniter States
11:55-12:15 Title: Tissue engineering and 3D printing of meniscal, tendon and musculoskeletal structures
Wilson Wang Ee Jen, National University of Singapore
12:15-12:35
Title: POT1 maintains hematopoietic stem cell activity by protecting against DNA damage and metabolic
alterations
Fumio Arai, Kyushu University, Japan
12:35-12:55 Title: Rejuvenation approach to treat chronic kidney diseases
Shrikant L. Kulkarni, Kulkarni Clinic, India
Lunch Break 12:55-13:55 @ Atrium Restaurant
Sessions:
Bone Tissue Engineering | Scaffolds in Regenerative Medicine | Cancer Therapy
Session Introduction
Session Chair: Alain Chapel, IRSN- Institute of Radioprotection and Nuclear Safety, France
Session Co-chair: Nelson Pinto, University of the Andes, Chile
13:55-14:15 Title: Advanced 3D vascularized in vitro models of human bone and muscle to study tumor cell extravasation
Matteo Moretti, IRCCS Galeazzi Orthopedic Institute, Italy
14:15-14:35 Title: Oncogenic transcription factor STAT3 as a target for cancer prevention and therapy
Gautam Sethi, National University of Singapore, Singapore
14:35-14:55 Title: A microRNA-638/ferritin gene: Pseudogene network regulates iron storage in prostate cancer
Yvonne Tay, National University of Singapore, Singapore
14:55-15:15 Title: Mapping cardiac progenitor cell fate via the mitochondria
Sang-Bing Ong, Duke-NUS Medical School, Singapore
15:15-15:35 Title: Adiponectin regulation of AMPK on oleanolic acid treated Sprague Dawley rats
Emmanuel Mukwevho, North West University, South Africa
Networking & Refreshment Break 15:35-15:50 @ Seletar Foyer
15:50-16:10
Title: Development and characterization of a bioactive porous collagen/β-tricalcium phosphate graft for
bone tissue engineering
Nafiseh Baheiraei, Tarbiat Modares University, Iran
16:10-16:30 Title: Biological potent heteroaryl ketone Schiff base and thorium(IV) complexes of 2-benzoaminothiazole
Neelima Mishra, Sanskriti University, India
Poster Presentations: 16:30-17:30
Poster Judge: Alain Chapel, IRSN- Institute of Radioprotection and Nuclear Safety, France
TSRM- 401 Title: Biophysical methods for scaffolds evaluation in rats
Elena A Gubareva, Kuban State Medical University, Russia
TSRM- 402 Title: Experience of decellularized diaphragm matrices creation on nonhuman primate model
Elena A Gubareva, Kuban State Medical University, Russia
TSRM- 403 Title: Cytotoxicity evaluation of biological and synthetic materials for bone regeneration
Elena V Kuevda, Kuban State Medical University, Russia
TSRM- 404 Title: Optimal cell sources for smooth and skeletal muscle matrices recellularization in rats
Elena V Kuevda, Kuban State Medical University, Russia
TSRM- 405 Title: Paricalcitol protects the kidney injury against radiocontrast in mice
Jin Hyun Kim, Gyeongsang National University Hospital, South Korea
TSRM- 406
Title: Poly (3-hydroxybutyrate)-chitosan/alumina nanowires electrospun nanocomposite scaffolds for
tissue engineering applications
Elahe Bahremandi Toloue, Isfahan University of Medical Sciences, Iran
TSRM- 407 Title: A bi-layer and biomimmetic scaffold for tissue engineering of vascular graft
Elahe Bahremandi Toloue, Isfahan University of Medical Sciences, Iran
TSRM- 408
Title: The role of oxidative stress as a mutational mechanism on telomeric deletion events
Raniah Alotibi, King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia
TSRM- 409 Title: Efficacy of umbilical cord lining mesenchymal stem cells for wound healing in diabetic murine model
Lim Fui Ping, National University of Singapore, Singapore
Panel Discussion
Awards & Closing Ceremony

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