Pathway Tools Tutorial on Metabolic Modeling using Flux Balance Analysis
- Science & Technology
- SRI International, Menlo Park CA
A steady-state metabolic flux model has been available from EcoCyc for several years. The model predicts the steady-state fluxes through the E. coli metabolic network using flux-balance analysis. The model can be used to predict growth or no growth of E. coli, and the cellular growth rate, under different nutrient conditions, and under different gene knock-outs. This webinar will illustrate how to run the model for different growth conditions and gene knock-outs, and will provide a basic overview of metabolic modeling and of the MetaFlux modeling component of Pathway Tools. MetaFlux can also be used to build metabolic flux models for other BioCyc organisms.
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