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The Injured Sentinel: Symposium in honour of Professor David Katz

UCL Division of Infection and Immunity

Thursday, May 5, 2011 from 9:00 AM to 6:00 PM (BST)

The Injured Sentinel: Symposium in honour of Professor...

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The symposium is being held in honour of Professor David Katz , Professor of Immunopathology  at UCL on the occasion of his retirement.  Professor Katz’s career spans the immunological era of the antigen presenting cell, and it is remarkable that these questions on which he has worked for several decades, and to which he has made many notable contributions, remain to this day at the forefront of research into many of the world’s most serious diseases.

The injured sentinel : the pathophysiology of the antigen presenting cell

The antigen presenting cell lies at the interface between innate and adaptive immunity, playing the role of sentinel  of the vertebrate microbial defence system.  This role exposes these cells to a unique challenge:  the antigen presenting cell must sense and respond to microbial invasion, and associated micro environmental damage and stress , while itself avoiding infection, injury and death. This symposium brings together an international interdisciplinary group of scientists, to explore the unique adaptations which allow cells to survive and function at this dangerous frontier, and to dissect the contributions of antigen presenting cell injury to disease.


9:30, Introduction    Prof. Sir John Tooke

9:45,  Session 1

Chair:  Prof. Sir Peter Lachmann, University of Cambridge, UK

Prof. David Hume, Roslin Institute, University of Edinburgh, UK: “The biology of CSF1”
Dr. Steffen Jung, Weizmann Institute of Science, Israel: “Dissecting Origins and Functions of Intestinal Mononuclear Phagocytes” ‐

****************COFFEE 10:45 – 11:15****************

11:15 Session 2

Dr. Michael Binks (GSK, UK) and Prof. Avrion Mitchison (UCL)

Dr. Paul Fairchild, Dept. Pathology, Oxford, UK: “Dendritic cells and pluripotency: Unlikely allies in the pursuit of immunotherapy” ‐
Dr. Marina Kreutz, University Hospital Regensburg, Germany: “Put to the acid test: immune cells in the tumor environment”
Prof. Adrian Thrasher, Institute of Child health, UCL, UK: “Actin up....too little and too much”

****************LUNCH 13:00 – 14:00****************

14:00 Session 3

Chair: Dr. Mohammad Ibrahim, Kings College London, UK

Dr. Martin Hewison, UCLA, USA: "Vitamin D and the immune System: the UCL legacy”
Dr. Phil King, University of Michigan, USA: “Genetic analysis of Ras signal transduction in the lymphatic system”
Prof. Benny Chain, UCL, UK: “Death, damage and dendrites”

****************TEA 15:45 – 16:15****************

16:15 Session 4

Co Chairs: Dr. Rob Miller, UCL and Prof. Saimon Gordon, University of Oxford, UK

Prof. Paul Kaye, University of York, UK: “Dendritic cells and macrophages: key players in remodeling the environment for antigen presentation during chronic infection”
Dr. Daniel Douek , NIH, USA: “HIV disease pathogenesis: more than just the virus”

Dr.Mahdad Noursadeghi, UCL, UK: “Study of hostpathogen interactions: From HIV infection of macrophages to the tuberculin skin test”

Closing remarks ‐ Prof. David Katz, UCL, UK


18:00 Drinks reception in the Wilkins Portico, Gower Street, UCL


Have questions about The Injured Sentinel: Symposium in honour of Professor David Katz? Contact UCL Division of Infection and Immunity
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When & Where

J Z Young Lecture Theatre
UCL Anatomy Building
Gower Street
WC1E 6BT London
United Kingdom

Thursday, May 5, 2011 from 9:00 AM to 6:00 PM (BST)

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UCL Division of Infection and Immunity

Contact: Isabel Lubeiro, i.lubeiro@ucl.ac.uk

  Contact the Organizer
The Injured Sentinel: Symposium in honour of Professor David Katz
London, United Kingdom Events Conference

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